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Články časopisu Current results of colorectal cancer screening and potential value of colon capsule endoscopy in the Czech Republic

Author of the article: O. Ngo, R. Chloupková, Suchánek Š., Zavoral M., Dušek L., O. Májek Source: Gastroenterologie a hepatologie | 5/2019 31. 10. 2019

News Primum non nocere applies not only in medicine: an ecological look at inhalers

According to estimates from the World Health Organization (WHO), around 65 million people worldwide suffer from mild to moderate forms of chronic obstructive pulmonary disease (COPD). The cornerstone of therapy is the inhalation administration of bronchodilator drugs. While there is no doubt that this therapy helps patients, what impact do the propellants in inhalation systems have on the global climate? And is there a sensible solution to this problem?

Source: COPD 25. 5. 2020

News Study COPDGene Redefines Diagnostic Criteria of Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease ranks among the top causes of morbidity and mortality worldwide. Current diagnostic criteria for the disease are based exclusively on spirometric examination. Increasing evidence, however, suggests that a significant number of patients show signs of chronic obstructive pulmonary disease without pathological findings on spirometry. The analysis of the COPDGene study thus proposes expanding the diagnostic criteria to include additional parameters.

Source: COPD 28. 5. 2020

News What impact do the symptoms of primary biliary cholangitis have on the patient and their quality of life

Primary biliary cholangitis (PBC) is a serious chronic cholestatic autoimmune liver disease that predominantly affects middle-aged women and can lead to end-stage liver failure and the need for transplantation. Several studies published this year show a reduction in the quality of life of patients with this disease due to its accompanying symptoms.

Source: Primary Biliary Cholangitis 12. 10. 2020

News Complex Impacts of Obesity on the Brains of People with Psychiatric Disorders

Obesity in individuals with bipolar disorder or schizophrenia is closely linked not only to higher mortality but also to worse progression of the psychiatric illness, lower response to psychiatric treatment, more frequent fatal outcomes (suicide), deterioration in cognitive functions, and structural brain damage. In his lecture at the XIV Congress of the Psychiatric Society of the Czech Medical Association J.E. Purkyně in Mikulov in June 2022, Professor Tomáš Hájek from Dalhousie University in Halifax, Canada, focused on these connections.

Source: Modern Treatment of Schizophrenia 18. 8. 2022

News One Step Closer to Understanding the Placebo Effect in Pain Treatment

Neuroscientists from the USA appear to have advanced our understanding of the placebo effect in pain relief. Their findings, recently published in Nature, open the possibility of influencing the described pain control pathway using drugs or neurostimulation.

Source: 12. 12. 2024

News Benefits of Time-Limited CLL Therapy

The advent of new targeted molecules has significantly influenced the possibilities of therapy for chronic lymphocytic leukemia (CLL) and are now an integral part of treatment regimens, including the 1st line. Individual therapeutic approaches and strategies based on them have their advantages and disadvantages as well as their target patient group, but the concept of time-limited treatment is increasingly gaining ground. Therapy today is significantly individualized, and its optimal choice is based on the assessment of various circumstances on the patient’s part and their disease.

Source: Chronic Lymphocytic Leukemia 5. 3. 2024

News Telmisartan, amlodipine, and chlorthalidone in a low-dose fixed triple combination –⁠ better control of target blood pressure values?

The secondary analysis of the TRIUMPH study, recently published in JAMA Cardiology, is likely the first published assessment of time spent in the target blood pressure (BP) range during antihypertensive treatment. This parameter was assessed in patients with moderate hypertension using a low-dose triple combination of antihypertensives (telmisartan 20 mg, amlodipine 2.5 mg, and chlorthalidone 12.5 mg) compared to usual care.

Source: Sartans in the Treatment of Hypertension 15. 6. 2022

News Safety and Tolerability of Bilastine in the Treatment of Chronic Urticaria in Children

Chronic urticaria is less common in pediatric patients compared to the acute form, but it always requires therapy due to bothersome chronic symptoms that reduce quality of life and disrupt daily activities of affected children. According to recent guidelines, the first-line treatment is non-sedating second-generation antihistamines, among which bilastine is included.

Source: Allergic Reactions 17. 8. 2020

News Hydrotherapy in the Treatment of Non-Healing Wounds

For the treatment of wounds, it is crucial how they are managed during the cleaning and granulation phases. For most non-healing wounds, so-called Hydrotherapy (treatment with hydroresponsive dressings) is suitable, which involves just two steps. The essence of Hydrotherapy is the maintenance of a moist environment and, if possible, a constant temperature in the wound.

Source: Wound Healing 10. 2. 2021

News Thyroid Disorder Screening in Pregnancy to Be Tested by Pilot Program Starting September

The expectations surrounding the trial launch of the screening program were discussed by Professor Michal Kršek, Chairman of the Czech Endocrinological Society ČLS JEP, on the occasion of the 12th annual “Thyroid Week”.

Source: Thyroid Disorders 8. 6. 2020

News Concise and Practical Recommendations for Optimal Care of Dental Prostheses

Millions of people around the world use full or partial dental prostheses. However, there are no standardized global procedures with guidelines on how to care for dental prostheses. Dentists and professional organizations, however, agree on one thing –⁠ the prosthesis must be cleaned regularly. The following practical recommendations are based on existing evidence and clinical studies that outline the best practices for cleaning dental prostheses.

Source: Optimal Care of Dentures 4. 5. 2020

News Myths Accompanying Therapy of Arterial Hypertension

Arterial hypertension is among the most common yet most underestimated diseases in the adult population. Misinterpretation of data and inadequate management of this disease can be caused, among other things, by an excessive amount of available clinical data and its incorrect analysis. Insufficient control of blood pressure (BP) is, however, one of the most significant factors in increased cardiovascular (CV) mortality.

Source: ACE inhibitory 18. 4. 2021

News What is the effectiveness of levodropropizine in the treatment of children's cough?

Levodropropizine represents an effective and safe option for the treatment of acute irritating cough in children. How does it compare to dropropizine and commonly used centrally acting antitussives?

Source: Cough Therapy 15. 2. 2022

News Forgotten Pulmonologists: COVID-19 Detection in Patients with Lung Disease

The Czech Pneumological and Phthisiological Society of ČLS JEP (ČPFS) submitted a request to the Ministry of Health of the Czech Republic on March 25, 2020, to allow pulmonologists to send patients with suspected COVID-19 directly for infection testing. In their statement, they also provide recommendations on how to manage care for patients with chronic lung diseases during the outbreak of the SARS-CoV-2 virus and how these patients should behave.

Source: Asthma under control 7. 4. 2020