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News Self-Administration of Romiplostim in Chronic Immune Thrombocytopenia: Analysis of 3 Studies

A post hoc analysis of 3 clinical studies showed that in adult patients with chronic immune thrombocytopenia (ITP), self-administration of romiplostim achieves comparable efficacy and safety as when the drug is administered by a healthcare professional.

Source: Immune Thrombocytopenia 23. 2. 2021

News The Role of the Physiotherapist in the Management of Hemophilia –⁠ Defining a New Normal

Historically, the role of physiotherapy in hemophiliacs was primarily to assist patients who developed severe hemophilic arthropathies resulting from recurrent untreated or inadequately treated bleeding. Today, it has also shifted to prevention as such, although it still plays a role in significant joint bleeding or when a hemophiliac needs to undergo surgery.

Source: Hemophilia with Movement 25. 2. 2021

News Improvement of Physical Functions in Patients with COPD in Routine Clinical Practice Using the Fixed Combination of Tiotropium/Olodaterol

The increase in exercise capacity using the fixed combination of tiotropium and olodaterol in the Respimat inhaler has already been demonstrated in clinical studies for patients with chronic obstructive pulmonary disease (COPD). Italian authors evaluated its benefit under real-world conditions and also focused on patient satisfaction with the inhaler.

Source: COPD 26. 2. 2021

News Thromboprophylaxis with Enoxaparin Reduces Mortality in Patients Hospitalized with COVID-19

Severe acute respiratory syndrome caused by COVID-19 is associated with a hypercoagulable state and an increased risk of thrombotic events. Since the beginning of the pandemic, thromboprophylaxis has been recommended for these patients despite initial insufficient evidence. In the fall of 2020, an observational study was published confirming the beneficial effect of enoxaparin on reducing mortality and the risk of ICU admission in patients with severe COVID-19.

Source: Thromboprophylaxis 11. 3. 2021

News Tolerability and Efficacy of Eye Drops with and without Preservatives −⁠ A Comparison in Routine Clinical Practice

Insufficient patient compliance due to intolerance of the ocular preparation is a major reason for changing treatment, such as switching to preservative-free drops. The aim of the international prospective and observational study was to assess the efficacy and local tolerability within a one-year therapy of preservative-free latanoprost compared to drops containing preservatives and to determine patient satisfaction at the midpoint of treatment. During the monitoring, 3 examinations were planned: one at the study entry and two follow-up visits (at 6 and 12 months).

Source: Treatment of Glaucoma 29. 6. 2020

News In vivo monitoring of corneal changes in patients treated with and without preservative-containing glaucoma medications

A study published last year by Italian authors monitored structural changes in the corneas of patients treated with preservative-free glaucoma medication for 3 years using confocal microscopy and compared them with changes observed in patients treated with preservative-containing medications.

Source: Treatment of Glaucoma 29. 6. 2020

News Incidence of Allergic Diseases in Children Probably Unrelated to Air Pollution

A recently published extensive meta-analysis of 7 cohorts of children aged 4 and 8 from 5 European countries investigated the relationship between air pollution at the child's place of residence and the incidence of allergic eczema, rhinoconjunctivitis, or asthma.

Source: Allergic Reactions 12. 6. 2020

News How to Communicate and Receive an Oncological Diagnosis

Communicating the truth about a patient's health condition does not have a very long tradition in the Czech Republic. The Czech healthcare system only began to emphasize this aspect, that is, honest and open communication between doctor and patient, several years after the Velvet Revolution.

Source: Lung Cancer 4. 6. 2020

News Can NOACs 'Compete' with Well-Managed Warfarin Treatment? Retrospective Data from Swedish Registers

The efficacy and safety of new oral anticoagulants (NOACs) in stroke prevention in atrial fibrillation have been proven by numerous studies. The quality of warfarin treatment, assessed by the 'time in therapeutic range' (TTR), ranged between 55% and 65% in these studies. The work of Swedish authors provides a comparison of patients treated with NOACs to a group on warfarin whose average TTR reached 70%.

Source: Anticoagulant Treatment 17. 2. 2020

News Persistence of Treatment with Secukinumab and Ixekizumab in Patients with Moderate to Severe Psoriasis

Although IL-17 targeted drugs are increasingly used in the treatment of moderate to severe psoriasis, we currently have limited data on patient persistence with these treatments.

Source: Biological Treatment 21. 2. 2020

News European Survey on Prophylactic Treatment of Chemotherapy-Induced Nausea and Vomiting Suggests Gaps in Practice and Ways to Improve

Using recommended guidelines for antiemetic prophylaxis can prevent chemotherapy-induced nausea and vomiting (CINV). Nurses play a significant role in administering prophylactic treatment for CINV. Therefore, a survey was conducted in 16 European countries among middle medical personnel to evaluate the use of recommended antiemetic prophylaxis in oncology practice and the obstacles to its administration.

Source: Antiemetic Therapy 13. 3. 2020

News Prognostic Significance of Subclinical Joint Changes on MRI in Hemophilia

Experience shows that monitoring joint changes, especially subclinical ones, is very necessary in the care of hemophiliacs. Unfortunately, conventional X-rays cannot detect early changes in joints. Magnetic resonance imaging (MRI) plays an indispensable role in detecting these changes.

Source: Hemophilia 16. 3. 2020

News Type of Pharmacological Thromboprophylaxis and Disease Stage as Risk Factors for Bleeding in Patients After Colorectal Cancer Surgery

Japanese authors of a study published last year in the World Journal of Surgical Oncology attempted to answer the question of whether the incidence of postoperative bleeding in patients undergoing elective surgery for colorectal cancer is associated with the type of pharmacological prophylaxis or the disease stage.

Source: Thromboprophylaxis 14. 3. 2020

News Direct Comparison of Ixekizumab and Adalimumab in Patients with Psoriatic Arthritis

The final results of the direct comparison of ixekizumab and adalimumab in the therapy of biologic-naïve patients with psoriatic arthritis were presented at the annual conference of the American College of Rheumatology (ACR/ARP) in November 2019 in Atlanta.

Source: Biological Treatment 6. 4. 2020

News Prevalence of Diabetics Among Patients with COVID-19 and the Impact of DM on the Course of Infection

Italian authors published the results of a meta-analysis of studies at the end of March, assessing the prevalence of diabetes among individuals infected with SARS-CoV2 and the impact of diabetes on the severity and progression of the infection.

Source: Modern Treatment of Diabetes 14. 4. 2020