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Obinutuzumab in the treatment of a patient with Waldenström macroglobulinemia and rituximab intolerance – a case report


Authors: Z. Adam;  M. Krejčí;  L. Pour;  M. Štork;  V. Sandecká;  Z. Král
Authors‘ workplace: Interní hematologická a onkologická klinika LF MU a FN Brno
Published in: Transfuze Hematol. dnes,27, 2021, No. 2, p. 160-165.
Category: Case Report
doi: https://doi.org/10.48095/cctahd2021160

Overview

Obinutuzumab is a new anti-CD20 monoclonal antibody predominantly used in the treatment of patients with chronic lymphocytic leukaemia and follicular lymphoma. In our case report, we describe successful treatment using obinutuzumab in a patient with Waldenström macroglobulinemia. This therapy was used as 4th line-treatment and led to complete bio­chemical and clinical response of Waldenström macroglobulinemia. Obitunuzumab could thus be useful option even in such a rare disease.

Keywords:

obinutuzumab – Waldenström macroglobulinemia


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Labels
Haematology Internal medicine Clinical oncology

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Transfusion and Haematology Today

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2021 Issue 2

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