Authors: J. Soukup; L. Krsková; V. Campr Authors‘ workplace: Ústav patologie a molekulární medicíny 2. LF UK a FN Motol, Praha Published in: Prakt. Lék. 2004; (10): 120-125 Category:
The knowledge about MALT lymphomas has dramatically changed in the last few years. Thegenesis of MALT lymphomas has become clearer, and new tools in modern diagnostics areavailable. This article, as a concise review, summarises the latest data and the clinical andmorphological characteristics with the aspect of routine diagnostics. The characteristic translocationt(11;18) and its chimeric transcript API2-MALT1 with antiapoptotic function isemphasised.
Key words: MALT lymphoma – BCL10 – API2 – MALT1 – IgH.
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