New Aspects in the Field of MALT Lymphomas of the Stomach

Czech version

Authors: J. Soukup; L. Krsková; V. Campr
Authors‘ workplace: Ústav patologie a molekulární medicíny 2. LF UK a FN Motol, Praha
Published in: Prakt. Lék. 2004; (10): 120-125
Category:

Overview

The knowledge about MALT lymphomas has dramatically changed in the last few years. Thegenesis of MALT lymphomas has become clearer, and new tools in modern diagnostics areavailable. This article, as a concise review, summarises the latest data and the clinical andmorphological characteristics with the aspect of routine diagnostics. The characteristic translocationt(11;18) and its chimeric transcript API2-MALT1 with antiapoptotic function isemphasised.

Key words:
MALT lymphoma – BCL10 – API2 – MALT1 – IgH.

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