McKittrick-Wheelock syndrom: Complication of rectal mucinous adenoma

Authors: R. Škuta;  M. Danaj;  I. Duda;  A. Dobrovodský
Authors‘ workplace: Chirurgická klinika FN Trnava a FZSP Trnavskej Univerzity, prednosta: Prof. MUDr. Miroslav Danaj, CSc.
Published in: Rozhl. Chir., 2012, roč. 91, č. 4, s. 246-248.
Category: Case Report


The McKittrick-Wheelock syndrome is a very rare complication of rectal villous adenoma, characterized by fluid and electrolyte hypersecretion from a rectal tumour, which can lead to acute renal failure.

We present a case review of a 67 –year old male patient hospitalised for profuse secretory diarrhea, with electrolyte dysbalance and progressive renal failure. A rectoscopic finding of massive rectal adenoma contributed to establishing the correct diagnosis. Resection of the affected part of the rectum resulted in rapid restoration from mineral imbalance and improvement of renal functions.

The reported case shows the necessity of interdisciplinar management and the importance of surgical treatment in patients with this rare diagnosis.

Key words:
McKittrick – Wheelock syndrom – acute renal failure – hypersecretory diarrhea – rectal mucinous adenoma – abdominoperineal rectal resection


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