Clostridium Difficile Colitis

Authors: D. Bergmann 1;  L. Horák 2
Authors‘ workplace: II. interní klinika FTNsP v Praze 1;  Chirurgická klinika FNKV a 3. LF UK Praha 2
Published in: Rozhl. Chir., 2008, roč. 87, č. 8, s. 409-412.
Category: Monothematic special - Original


The authors present a detailed study of Clostridium difficile-induced conditions and desribe their pathogenesis, diagnostics, and treatment. Considering the extensive use of antibiotics and increasing numbers of immunocompromized patients, it can be expected that surgeons will face this infection, which was practically unknown a few years ago, more often in future. Based on the above facts, the authors consider important to inform the surgical profession about the problematics.


1. Joyce, A. M., Burns, D. L. Recurrent Clostridium difficle colitis Tackling a tenacious nosocomial infection. Postgraduate Medicine. Minneapolis: Nov 2002. Vol. 112, Iss 5, pg. 53.

2. Bergmann, D., Koten, J., Beneš, Z., et al. Pseudomembranózní kolitida. Vnitř. Lék., 2007; 53(10): 645–652.

3. Kuijper, E. J., Coignard, B., Tüll, P., et al. Emergence of Clostridium difficile-associated disease in North America and Europe. Clin. Microb. Infect., 2006; 12 (s6), 2–18.

4. Beneš, J., Sýkorová, B. Kolitida vyvolaná Clostridium difficile. Zpráva z kongresu ICAAC 2006. Klin. mikrobiol. inf. lék., 2006; 12(6): 247–251.

5. Delmée, E. Laboratory diagnosis of Clostridium difficile disease. Clin. Microbiol. Infect., 2001; 7: 411–416.

6. Johal, S. S., Hammond, J., Solomon, K., et al. Clostridium difficile associated diarrhoea in hospitalised patients: onset in the community and hospital and role of flexible sigmoidoscopy. Gut, 2004; 53: 673–677.

7. Surawicz C. M. Antibiotic-Associated Diarrhea and Pseudomembranous Colitis: Are They Less Common with Poorly Absorbed Antimicrobials? Chemotherapy, 2005: 51 (suppl 1): 81–89.

8. Ki, S. L., Woon, G. S. Myoung, K. J., Hyoung, S. K., Hee, S. K., Chi, J. P., Ja Y. L., Kyung, H. K., JoonYong, P. Jin, H. L., Hak, Z. K., Sung, J. C., Jae, Y. Y. Who are Susceptible to Pseudomembranos Collitis Among Patients With Presumed Antibiotic-Associated Diarrhea? Dis. Colon Rectum, 2006: 49: 1552–1558.

9. Poutanem, S. M., Simor, A. E. Clostidium Difficile-associated diarrhea in adults. Canadian Medical Association Journal: Jul 6, 2004: 171: 51–56.

10. Said, F. Y., Tonia, M. Y.-F., Nizar, N. Z., Darrel, S. P. Clostridium difficile-Associated Diarrhea and Colitis. Mayo Clinic Proceedings: Jul 2001: 76: 725–730.

Surgery Orthopaedics Trauma surgery
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