Intraoperative use of enhanced contact endoscopy for evaluation of laryngeal mucosal lesions, validation of ELS classification
Authors:
Anna Švejdová 1,2; Michal Homoláč 1,2; Peter Kántor 3,4; Michal Černý 1,2; Jana Šatanková 1,2; Lucie Zeinerová 1; Jan Mejzlík 1,2; Jana Krtičková 1,2; Viktor Chrobok 1,2
Authors‘ workplace:
Klinika otorinolaryngologie a chirurgie hlavy a krku, FN Hradec Králové
1; Univerzita Karlova, LF v Hradci Králové
2; Klinika otorinolaryngologie a chirurgie hlavy a krku, FN Ostrava
3; Katedra kraniofaciálních oborů, LF OU, Ostrava
4
Published in:
Otorinolaryngol Foniatr, 73, 2024, No. 1, pp. 28-36.
Category:
Original Article
doi:
https://doi.org/10.48095/ccorl202428
Overview
Introduction: Enhanced contact endoscopy (ECE) – combination of contact endoscopy and NBI (narrow-band imaging) or IMAGE1 S, is a non-invasive optical technique used for assessment of superficial vascular changes of mucosal lesions in high magnification. Aim: The aim of our study was to evaluate the diagnostic value of ECE in an intraoperative settlement and validation of the ELS classification. Methods: Patients with laryngeal lesions underwent direct laryngoscopy with a structured assessment of the lesion using white light, NBI and ECE. Lesions were classified according to the European Laryngological Society Classification that divides the vascular pattern changes into longitudinal (unsuspicious) and perpendicular (suspicious). Evaluation was correlated with histopathology. Results: 60 patients with 76 lesions were enrolled. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy for NBI assessment reached 71.4%, 100%, 100%, 53.8% and 78.6%, resp., k index of 0.556. Sensitivity, specificity, PPV, NPV and accuracy for ECE reached 86.4%, 89.5%, 95.0%, 73.9% and 87.3%, k index of 0.716. Additional 20% (9/45) of the leukoplakias could be assessed with ECE compared to NBI. Conclusions: Our data support the assumption that ECE is a useful tool for pre-histological examination of mucosal lesions, however it cannot fully replace biopsy sampling. ECE shows higher accuracy in detecting malignant lesions compared to NBI and can be especially helpful in the assessment of vocal fold leukoplakia.
Keywords:
squamous cell carcinoma – enhanced contact endoscopy – narrow-band imaging – laryngeal mucosal lesions – leukoplakia
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ORCID autorů
Přijato k recenzi: 29. 5. 2023
Přijato k tisku: 25. 7. 2023
MUDr. Anna Švejdová
Klinika otorinolaryngologie a chirurgie hlavy a krku
LF UK a FN Hradec Králové
Sokolská 581
500 05 Hradec Králové
anna.svejdova@fnhk.cz
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Audiology Paediatric ENT ENT (Otorhinolaryngology)Article was published in
Otorhinolaryngology and Phoniatrics
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