Fine-needle aspiration biopsy and Bethesda classification in the diagnostics of the tumours of the thyroid gland – a retrospective study
Authors:
V. Kubec 1; M. Riant 1; P. Škopek 1; P. Hrabačka 1; M. Horáková 2,3
Authors‘ workplace:
Bioptická laboratoř s. r. o., Plzeň
2; Šiklův ústav patologie LF UK a FN Plzeň
3
Published in:
Otorinolaryngol Foniatr, 73, 2024, No. 1, pp. 16-21.
Category:
Original Article
doi:
https://doi.org/10.48095/ccorl202416
Overview
Introduction: Thyroid nodule is a pathology with a prevalence of 19–68% of the population, with a thyroid gland carcinoma proven in 7–15% of these cases. Bethesda classification is a standardized system for cytology findings evaluation. Aim of work: The aim of our work was to compare a predicted preoperative diagnosis including Bethesda classification and the final histology results, to define malignancy risk for Bethesda categories and to compare our findigs with foreign papers. Material and methods: A retrospective, observational study. In a group of 330 patients with performed operation on the thyroid gland (total thyroidectomy or hemithyroidectomy) at the ENT department of the University hospital in Pilsen between 2016 and 2017 there was a group of 180 patients (147 female and 33 male patients) with preoperatively known Bethesda category. We have compared an expected diagnosis and postoperatively known histology diagnosis, determined a risk of malignancy rate for each category of Bethesda classification and compared our results with a foreign literature. Results: In the group of our patients, we have determined a risk of malignancy rate for Bethesda I. category as 14.29%, same as for Bethesda II. For Bethesda III. as 15.79%, Bethesda IV. as 10.64%, Bethesda V. as 52.17% and Bethesda VI. category as 100%. Conclusion: Fine- -needle aspiration biopsy of thyroid gland nodules is a basic diagnostic method, which facilitates categorization and stratification of a risk of malignancy in cytological findings. In our group of patients, a risk of malignancy rate differs in Bethesda I. and II. category, our risk of malignancy rate is higher compared to foreign literature, which, we believe, is a statistical error due to a rather small set of patients.
Keywords:
thyroid nodule – Bethesda classification – fine-needle aspiration biopsy – risk of malignancy rate
Sources
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Přijato k recenzi: 6. 10. 2022
Přijato k tisku: 15. 12. 2022
MUDr. Vojtěch Kubec
Otorhinolaryngologická klinika
LF UK a FN Plzeň
Edvarda Beneše 1128/13
305 99 Plzeň-Bory
kubecv@fnplzen.cz
Labels
Audiology Paediatric ENT ENT (Otorhinolaryngology)Article was published in
Otorhinolaryngology and Phoniatrics
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