Solitary Fibrous Tumour of the Parotid Gland. Case Report and Review of the Literature


Authors: K. Macháleková 1;  T. Feltsan 2;  M. Polakovič 3;  P. Šuráň 1;  C. Bíró 1;  Ľ. Malíček 2;  K. Kajo 1
Authors‘ workplace: Ústav patológie, Onkologický ústav sv. Alžbety, s. r. o., Bratislava 1;  Klinika stomatológie a maxilofaciálnej chirurgie, LF UK a Onkologický ústav sv. Alžbety, s. r. o., Bratislava 2;  II. Rádiologická klinika LF UK a Onkologický ústav sv. Alžbety, s. r. o., Bratislava 3
Published in: Otorinolaryng. a Foniat. /Prague/, 68, 2019, No. 2, pp. 118-122.
Category: Case Reports

Overview

Solitary fibrous tumor (SFT) is a rare mesenchymal tumor, which can be extremely rarely found also in the parotid gland. In the article, the authors describe a case of a 39-year-old man with a clearly bounded and painless tumor, sized 4x3cm and located in the angle of the left mandible. According to the histomorphological characteristics and immunohistochemical stains of CD34, bcl-2 and CD99, the tumor was diagnosed as SFT. Due to the finding of some atypical features, it was classified as a tumor with an unclear biological potential. In the discussion there are confronted recorded clinical and histomorphological characteristics of the lesion, differential diagnostic fields, prognostic aspects and therapeutic possibilities with previously known literary data about SFT.

Keywords:

solitary fibrous tumor – parotid gland – immunohistochemistry


Sources

1. Bauer, J., Miklos, A. Z., Thompson, L. D. R.: Parotid gland solitary fibrous tumor: a case report and clinicopathologic review of 22 cases from the literature. Head and Neck Pathol, 2012, 6, s. 21-31.

2. De Perrot, M., Fischer, S., Bründler, M. A. et al.: Solitary fibrous tumors of the pleura. Ann Thorac Surg, 74, 2002, s. 285-293.

3. Fletcher, C. D. M., Bridge, J. A., Lee, J. C.: Extrapleural solitary fibrous tumor. In: Fletcher, C. D. M., Bridge, J. A., Hogendoorn, P. C. W. et al. editors. WHO classification of tumours of soft tissue and bone. IARC Press, Lyon, 2013, s. 80-82.

4. Gengler, C., Guillou, L.: Solitary fibrous tumour and haemangiopericytoma: evolution of a concept. Histopathology, 48, 2006, 1, s. 63-74.

5. Klempeler, P., Rabin, C. B.: Primary neoplasms of the pleura: a report of five cases. Arch Pathol, 11, 1931, s. 385-412.

6. Lindberg, M. R.: Solitary fibrous tumor. In Lindberg, M. R., Luca, D., Gardner, J. M. et al editors. Soft tissue tumors. 2nd ed., Elsevier, Philadelphia, 2016, s. 176-183.

7. Rais, M., Kessab, A., Sayad, Z. et al.: Solitary fibrous tumor occurring in the parotid gland: a case report. BMC Clinical Pathol, 17, 2017, s. 22.

8. Robinson, L. A.: Solitary fibrous tumor of the pleura. Cancer Control, 13, 2006, 4, s. 264-269.

9. Rodriguez-Gil, Y., Gonzalez, M. A., Carcavilla, C. B. et al.: Lines of cell differentiation in solitary fibrous tumor: an ultrastructural and immunohistochemical study of 10 cases. Ultrastruct Pathol, 33, 2009, 6, s. 274-285.

10. Sato, J., Asakura, K., Yokoyama, Y. et al.: Solitary fibrous tumor of the parotid gland extending to the parapharyngeal space. Eur Arch Otorhinolaryngol, 255, 1998, 1, s. 18-21.

11. Smith, S. C., Googing, W. E., Elkins, M. et al.: Solitary fibrous tumor of the head and neck: a multiinstitutional clinicopathologic study. Am J Surg Pathol, 41, 2017, 12, s. 1642-1656.

12. Tai, H. C., Chuang, I. C., Chen, T. C. et al.: NAB2-STAT6 fusion types account for clinicopathological variations in solitary fibrous tumors. Mod Pathol, 28, 2015, 10, s. 1324-1335.

13. Yang, X. J., Zheng, J. W., Ye, W. M. et al.: Malignant solitary fibrous tumors of the head and neck: a clinicopathological study of nine consecutive patients. Oral Oncol, 45, 2009, 8, s. 678-682.

14. Zhou, Y., Zheng, J., Zhu, Q. et al.: Solitary fibrous tumor of the salivary gland: a case report. Oncol Lett, 11, 2016, 1, s. 901-903.

15. Zubor, P., Kajo, K., Szunyogh, N. et al.: A solitary fibrous tumor in the broad ligament of the uterus. Pathol Res Pract, 203, 2007, 7, s. 555-560.

Labels
Audiology Paediatric ENT ENT (Otorhinolaryngology)
Login
Forgotten password

Don‘t have an account?  Create new account

Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account