Metastatic Breast Cancer as a Rare Cause of Deafness and Eyesight Deterioration: Case Report


Authors: A. Srba 1;  D. Kovář 1;  J. Astl 1;  L. Nováček 2,3;  R. Svoboda 2;  J. Pašta 3
Authors‘ workplace: Klinika otorinolaryngologie a maxilofaciální chirurgie 3. LF UK a ÚVN Praha 1;  Oční oddělení ÚLZ Praha 2;  Oční klinika 1. LF UK a ÚVN Praha 3
Published in: Otorinolaryng. a Foniat. /Prague/, 68, 2019, No. 2, pp. 114.
Category: Case Reports

Overview

The article presents an uncommon case of deafness. A patient with symptoms of acute rhinosinusitis with mastoiditis was hospitalized for antibiotics therapy and surgery. Objective examinations were characterized by muco-purulent nasal discharge, mucous middle ear secretion of both sides and starting protrusion of right eyeball. CT and MRI images were with complete obstruction of all nasal cavities and mastoids. The patient suffered from significant deterioration of hearing, up to deafness on the right side. After the FESS, there was no regression of the pathological condition. The results of histological examination of polypous tissue revealed the presence of advanced breast cancer with distant metastasis (stage IV). The first signs of this disease were acute pansinusitis with mastoiditis, eyeball protrusion and significant deterioration of hearing.

Keywords:

deafness – pansinusitis – mastoiditis – FESS – breast carcinoma – metastasis


Sources

1. Clamp, P. J., Jardine, A. H.: Mastoiditis secondary to metastatic lung carcinoma: case report and literature review. J Laryngol Otol, 125, 2011, 11, s. 1173-1175.

2. Fyrmpas, G., Televantou, D., Papageorgiou, V. et al.: Unsuspected breast carcinoma presenting as orbital complication of rhinosinusitis. Eur Arch Otorhinolaryngol, 265, 2008, 8, s. 979-982.

3. Johnston, J. L.: Parasellar syndromes. Curr Neurol Neurosci Rep, 2, 2002, 5, s. 423-431.

4. Mehrgou, A., Akouchekian, M.: The importance of BRCA1 and BRCA2 genes mutations in breast cancer development. Med J Islam Repub Iran, 30, 2016, s. 369.

5. Mitsuya, K., Nakasu, Y., Horiguchi, S. et al.: Metastatic skull tumors: MRI features and a new conventional classification. J Neurooncol, 104, 2011, 1, s. 239-245.

6 Petruželka, L., Konopásek, B.: Klinická onkologie. 1. vydání, Praha, Univerzita Karlova v Praze, Karolinum, 2003.

7. Popiel, M., Mroz-Klimas, D., Kasprzak, R. et al.: Mammary carcinoma - current diagnostic methods and symptomatology in imaging studies. Pol J Radiol, 77, 2012, 4, s. 35-44.

8. Redig, A. J., McAllister, S. S.: Breast cancer as a systemic disease: a view of metastasis. J Intern Med, 274, 2013, 2, s. 113-126.

9. Reimann, K., Schulze, M., Adam, P. et al.: Nasennebenhöhlenmetastasen eines Mammakarzinoms. HNO, 59, 2011, 9, s. 915-917.

10. Sharma, G. N., Dave, R., Sanadya, J. et al.: Various types and management of breast cancer: an overview. J Adv Pharm Technol Res, 1, 2010, 2, s. 109-126.

11. Suva, L. J., Griffin, R. J., Makhoul, I.: Mechanisms of bone metastases of breast cancer. Endocr Relat Cancer, 16, 2009, 3, s. 703-713.

12. Vlachostergios, P. J., Voutsadakis, I. A., Papandreou, C. N.: Orbital metastasis of breast carcinoma. Breast Cancer (Auckl), 3, 2009, s. 91-97.

Labels
Audiology Paediatric ENT ENT (Otorhinolaryngology)
Login
Forgotten password

Don‘t have an account?  Create new account

Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account