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Practical recommendations for the management of children after kidney and liver transplantation


Authors: Jakub Zieg 1;  David Bauer 2;  Vlasta Krejčová 1;  Lucie Gonsorčíková 2
Authors‘ workplace: Pediatrická klinika 2. LF UK a FN Motol, Praha 1;  Pediatrická klinika 1. LF UK a FTN, Praha 2
Published in: Čas. Lék. čes. 2022; 161: 296-302
Category: Guidelines

Overview

The number of pediatric solid organ transplantations is growing. This therapy leads often to better quality of life but also brings some specific complications. Our review summarizes practical recommendations for long-time care of the children after kidney and liver transplantation. The knowledge of the issues related to transplantation is essential for the first contact physicians, whose cooperation with transplant centre contributes highly to adequate management of these children.

Keywords:

kidney transplantation – liver transplantation – adherence – sport – medication


Sources

1.    Zieg J, Skálová S. Dětská nefrologie do kapsy. Mladá fronta, Praha, 2019.

2.    Spada M, Riva S, Maggiore G et al. Pediatric liver transplantation. World J Gastroenterol 2009; 15: 648–674.

3.    Balani SS, Jensen CJ, Kouri AM et al. Induction and maintenance immunosuppression in pediatric kidney transplantation-Advances and controversies. Pediatr Transplant 2021; 25 7: e14077.

4.    Miloh T, Barton A, Wheeler J et al. Immunosuppression in pediatric liver transplant recipients: unique aspects. Liver Transpl 2017; 23: 244–256.

5.    Daschner M. Drug dosage in children with reduced renal function. Pediatr Nephrol 2005; 20: 1675–1686.

6.    Christians U, Jacobsen W, Benet LZ et al. Mechanisms of clinically relevant drug interactions associated with tacrolimus. Clin Pharmacokinet 2002; 41: 813–851.

7.    DeAngelis M, Martin K, Williams A et al. Most commonly asked questions from parents of pediatric transplant recipients. Pediatr Clin North Am 2010; 57: 611–622.

8.    Pneumocystis jiroveci (formerly Pneumocystis carinii). Am J Transplan 2004; 4 (Suppl. 10): 135–141.

9.    Buder K, Zirngibl M, Bapistella S et al. Current practice of antithrombotic prophylaxis in pediatric kidney transplantation-Results of an international survey on behalf of the European Society for Paediatric Nephrology. Pediatr Transplant 2020; 24: e13799.

10.  Lau KK, Giglia L, Chan H et al. Management of children after renal transplantation: highlights for general pediatricians. Transl Pediatr 2012; 1: 35–46.

11.  Allen UD, Preiksaitis JK; AST Infectious Diseases Community of Practice. Post-transplant lymphoproliferative disorders, Epstein-Barr virus infection, and disease in solid organ transplantation: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice. Clin Transplant 2019; 33: e13652.

12.  Scaggs Huang FA, Danziger-Isakov L. Infectious disease risks in pediatric renal transplantation. Pediatr Nephrol 2019; 34: 1155–1166.

13.  Katz DT, Torres NS, Chatani B et al. Care of pediatric solid organ transplant recipients: an overview for primary care providers. Pediatrics 2020; 146: e20200696.

14.  Guggenheimer J, Eghtesad B, Stock DJ. Dental management of the (solid) organ transplant patient. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003; 95: 383–389.

15.  Fonseca-Aten M, Michaels MG. Infections in pediatric solid organ transplant recipients. Semin Pediatr Surg 2006; 15: 153–161.

16.  Pham YH, Miloh T. Liver transplantation in children. Clin Liver Disease 2018; 22: 807–821.

17.  Dharnidharka VR, Fiorina P, Harmon WE. Kidney transplantation in children. N Engl J Med 2014; 371: 549–558.

18.  Bunnapradist S, Neri L, Wong W et al. Incidence and risk factors for diarrhea following kidney transplantation and association with graft loss and mortality. Am J Kidney Dis 2008; 51: 478–486.

19.  Sundaram SS, Alonso EM, Zeitler P et al. Obesity after pediatric liver transplantation: prevalence and risk factors. J Pediat Gastroenterol Nutr 2012; 55: 657–662.

20.  Ladhani M, Lade S, Alexander SI et al. Obesity in pediatric kidney transplant recipients and the risks of acute rejection, graft loss and death. Pediatr Nephrol 2017; 32: 1443–1450.

21.  Ghirardo G, De Franceschi M, Vidal E et al. Transplant renal artery stenosis in children: risk factors and outcome after endovascular treatment. Pediatric Nephrol 2014; 29: 461–467.

22.  Seeman T, Feber J. Should ACE inhibitors or calcium channel blockers be used for post-transplant hypertension? Pediatric Nephrol 2021; 36: 539–549.

23.  Zhang H, Zheng Y, Liu L et al. Steroid avoidance or withdrawal regimens in paediatric kidney transplantation: a meta-analysis of randomised controlled trials. PLoS One 2016; 11: e0146523.

24.  Fine RN. Growth following solid organ transplantation in childhood. Clinics (Sao Paulo) 2014; 69 (Suppl. 1): 3–7.

25.  Prokai A, Fekete A, Kis E et al. Post-transplant diabetes mellitus in children following renal transplantation. Pediatr Transplant 2008; 12: 643–649.

26.  Hathout E, Alonso E, Anand R et al. Post-transplant diabetes mellitus in pediatric liver transplantation. Pediatr Transplant 2009; 13: 599–605.

27.  Cohen E, Korah M, Callender G et al. Metabolic disorders with kidney transplant. Clinical J Am Society Nephrol 2020; 15: 732–742.

28.  Grundman JB, Wolfsdorf JI, Marks BE. Post-transplantation diabetes mellitus in pediatric patients. Hormone Res Paediatr 2020; 93: 510–518.

29.  Robinson CH, Coughlin CC, Chanchlani R et al. Post-transplant malignancies in pediatric organ transplant recipients. Pediatr Transplant 2021; 25: e13884.

30.  Dreno B. Skin cancers after transplantation. Nephrol Dial Transplant 2003; 18: 1052–1058.

31.  Baker A, Frauca Remacha E, Torres Canizales J et al. Current practices on diagnosis, prevention and treatment of post-transplant lymphoproliferative disorder in pediatric patients after solid organ transplantation: results of ERN TransplantChild Healthcare Working Group Survey. Children (Basel) 2021; 8: 661.

32.  Amatya K, Monnin K, Steinberg Christofferson E. Psychological functioning and psychosocial issues in pediatric kidney transplant recipients. Pediatr Transplant 2021; 25: e13842.

33.  Shiboski CH, Kawada P, Golinveaux M et al. Oral disease burden and utilization of dental care patterns among pediatric solid organ transplant recipients. J Public Health Dent 2009; 69: 48–55.

34.  Hemsworth S, Pizer B. Pet ownership in immunocompromised children – a review of the literature and survey of existing guidelines. Eur J Oncol Nurs 2006; 10: 117–127.

35.  Coughlin CC, Perez M, Kumar MG et al. Skin cancer risk education in pediatric solid organ transplant patients: an evaluation of knowledge, behavior, and perceptions over time. Pediatr Transplant 2017; 21: e12817.

36.  Lindelof B, Granath F, Dal H et al. Sun habits in kidney transplant recipients with skin cancer: a case-control study of possible causative factors. Acta Derm Venerol 2003; 83: 189–193.

37.  Bartosh S, Dipchand A, Chavers B, Pediatric Kidney Transplantation. A Guide for Patients and Families. American Society of Transplantation, 2015. Dostupné na: www.erknet.org/patient_info/Pediatric_Kidney_Transplantation_BrochureAST__-_final_copy_2015-06-27_0.pdf

38.  Kreuzer M, Prufe J, Tonshoff B et al. Survey on management of transition and transfer from pediatric- to adult-based care in pediatric kidney transplant recipients in Europe. Transplantat Direct 2018; 4: e361.

Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management

Article was published in

Journal of Czech Physicians

Issue 7-8

2022 Issue 7-8

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