Lymphogranuloma venereum
Authors:
Daniela Vaňousová 1; Hana Zákoucká 2; Jaroslav Marvan 3; David Jilich 4; Naděžda Vojáčková 1; Jana Hercogová 1; Ladislav Machala 5
Authors‘ workplace:
Dermatovenerologická klinika 2. LF UK a Centrum pro pohlavní nemoci Nemocnice Na Bulovce, Praha
1; Národní referenční laboratoř pro chlamydie, Státní zdravotní ústav, Praha
2; Chirurgická klinika a Nemocnice Na Bulovce, Praha
3; Klinika infekčních a tropických nemocí 1. LF UK a Nemocnice Na Bulovce, Praha
4; Klinika infekčních, parazitárních a tropických nemocí 3. LF UK a Nemocnice Na Bulovce, Praha
5
Published in:
Čas. Lék. čes. 2012; 151: 523-526
Category:
Review Articles
Overview
Lymphogranuloma venereum is a sexually transmitted disease caused by serovars L1–3 of Chlamydia trachomatis. This infection was originally endemic in tropics and transmitted predominantly by heterosexual contact but since the beginning of the century it spreads in industrialized countries mainly among men having sex with men causing them severe proctitis. In the Czech Republic the first case was diagnosed in 2011. Lymphogranuloma venereum can resemble other forms of anorectal disorders inclusive inflammatory bowel diseases and thus it must be included into differential diagnostic considerations. Definitive diagnosis is based on detection of specific serovars of Chlamydia trachomatis by polymerase chain reaction. In patients with lymphogranuloma venereum it is also necessary to exclude other sexually transmitted diseases, particularly syphilis, HIV and also hepatitis C. The therapy of choice is doxycycline administered for three weeks.
Key words:
Chlamydia trachomatis, serovar L, biovar LGV, proctitis, lymphogranuloma venereum, HIV.
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