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Ručka D, Lubanda JC, Karetová D, Skalická L, Vařejka P, Mrázek V, Linhart A. Carotid plaque exulcerated


Authors: David Ručka;  Jean Claude Lubanda;  Debora Karetová;  Lenka Skalická;  Petr Vařejka;  Vratislav Mrázek;  Aleš Linhart
Authors‘ workplace: Univerzita Karlova v Praze, 1. lékařská fakulta a VFN, II. interní klinika kardiologie a angiologie
Published in: Čas. Lék. čes. 2011; 150: 106-109
Category: Case Report

Overview

The authors report a case of a 77 years old male patient with mild stenosis of the carotid artery caused by an exulcerated plaque in the carotid bifurcation. The patient presented with recurrent ipsilateral strokes which were treated with intravenous thrombolysis. A brief review of the literature related to the management of unstable exulcerated carotid plaque is presented in this article with emphasis on current treatment options. Carotid endarterectomy if often performed in such cases. However, the outcome of the procedure remains still very controversial. In the described case, conservative approach using optimal medical treatment with lipid lowering agents, antiplatelet and antihypertensive therapy was chosen mainly because of patient preference and resulted in favourable outcome.

Key words:
atherosclerosis, unstable carotid plaque, carotid artery stenosis, carotid endarterectomy.

Ru.


Sources

1. Spáčil J. Extracranial carotid artery stenoses. Čas Lék čes 2003; 142: 10–13.

2. Eliasziw M, Streifler JY, Fox AJ, et al. Significance of plaque ulceration in symptomatic patiens with hight-grade carotid stenosis. North American Symptomatic Carotid Endarterectomy Trial. Stroke 1994; 25: 304–308.

3. Streifler JY, Eliasziw M Fox AJ, et al. Angiographic detection of carotid plaque ulceration: comparison with surgical observations in a multicenter study. Stroke 1994; 25: 1130–1132.

4. Rothwell PM, Gibbon R, Warlow CP. Interrelation between plaque surface morphology and degree of stenosis on carotid angiograms and the risk of ischemic stroke in patiens with symptomatic carotid stenosis. Stroke 2000; 31: 615–621.

5. DeMarco JK, Ota H, Underhill HR. Carotid plaque imaging and contrast-enhanced MR angiography identifies lesions associated with recent ipsilateral thromboembolic symptoms: An in vivo study at 3T. Am J Neuroradiol 2010; 31(8): 1395–1342.

6. Saba L, Caddeo G, et al. CT and ultrasound in the study of ulcerated carotid plague compared with surgical results: Potentialities and advantages of multidetector row CT angiography, 2007; 28: 1061–1066.

7. De Bray JM, Baud JM, Dauzat M. Consensus concerning the morphology and the risk of carotid plaques. Cerebrovasc Dis 1997; 7: 289–296.

8. Lovett JK, Gallagher PJ, Hands LJ, et al. Histological correlates of carotid plague surface morphology on lumen contrast imaging. Circulation 2004; 1100: 2190–2197.

9. Goričan K, Chochola M, Vařejka P, Bartůněk P. Value of duplex ultrasound examination of the proximal part of the common carotid artery. Čas Lék čes 2005; 144 (Suppl 1): 27–29.

10. Sitzer M, Miller W, Siebler M, et al. Plaque ulceration and lumen trombus are the main sources of cerebrál microemboli in hight-grade internal artery stenosis. Stroke 1995; 26(7): 1231–1233.

11. Moore WS, Boren C, Malone JM, et al. Natural history of nonstenotic asymptomatic ulcerative lesion of the carotid artery. Arch Surg 1978; 113: 1352–1359.

12. Dixon S, Pais O, Raviola C, et al. Natural history of nonstenotic, asymptomatic ulcerative lesions of the carotid artury. Arch Surg 1982; 117: 1493–1498.

13. Moore WS, Hall AD. Importace of emboli from karotid bifurcation in pathogenesis of cerebrál ischemic attacks. Arch Surg 1970; 101: 708–716.

14. Wechsler LR. Ulceration and carotid artery disease. Stroke 1988; 19: 650–653.

15. Rutherford RB, et al. Vascular surgery, Sixth Edition. Phila­delphia: John F. Kennedy 2005

16. Sacco RL, Adams R, Albert G, Alberts MJ, et al. Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: A statement for healthcare professionals from the american heart association/american stroke association council on stroke: Co.sponsored by the council on cardiovascular radiology and intervention: The American Academy of Neurology affirms the value of this guideline. Stroke 2006; 37: 577–617.

17. Diener HC, Boguslavsky J, Bras LM, et al. Aspirin and clopidogrel compared with alone after recent ischaemic atttack in high-risc patiens (MATCH): randomized, double-blind, placebo-controlled trial. Lancet 2004; 364: 331–337.

18. Goričan K, Romaniv S,Veiser T. Mobile trombus at the origin of the internal carotid artery. Čas Lék čes 2004; 143: 630–632.

19. Markus HS, Droste DW, Kaps M, Larrue V, et al. Dual antiplatelet therapy with clopidogrel and aspirin in symptomatic Carotid stenosis evaluated using doppler embolic signal detection. The clopidogrel and aspirin for reduction of emboli in symptomatic carotid stenosis (CARESS) trial. Circulation 2005; 111: 2233–2240.

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Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management
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