Orthopaedic Treatment of Osteolytic Lesions in Long Bones of Multiple Myeloma Patients

Authors: E. Šťastný;  R. Chaloupka 1;  T. Trč;  M. Handl
Authors‘ workplace: Ortopedická klinika dětí a dospělých FNM, Praha ;  Ortopedická klinika FN, Brno–Bohunice 2
Published in: Čas. Lék. čes. 2007; 146: 35-39
Category: Review Article


Treatment of the multiple myeloma has developed rapidly during the last years. Introduction of autologous transplantation in the ninetieth of the previous century radically prolonged the period of survival. New types of drugs influencing the metabolism of myeloma cells and their adhesion to neighbouring tissues brought promising improvement of the therapy results. In spite of the optimistic view, multiple myeloma represents an incurable disease and its multiplex manifestations in the skeleton endanger the patient by pathologic fractures and significant decrease of the duality of life. In the article we aimed to identify reliability of individual diagnostic methods. The manifold symptomatology of the disease implies the necessity of complex evaluation of the patient’s status, considering the risks of surgical intervention and the possibility of related complications. In the surgical treatment selection of the most appropriate approach and type of implant related to the prognosis of survival with the aim to improve the quality of life of the patient.

Key words:
multiple myeloma, Mirels score, osteolytic lesion, stabilization of the skeleton.

Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management fenix.admin.empty

Article was published in

Journal of Czech Physicians

Most read in this issue

This topic is also in:

Forgotten password

Don‘t have an account?  Create new account

Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.


Don‘t have an account?  Create new account