Healthy and Psychosocial Aspects of Quality of Life in Patients Undergoing Autologous Progenitor Stem Cell Transplantation

Overview

Background.
The haematopoietic stem cell transplantation is a specific therapy used not only for the treatment of haematooncological diseases, but also for the treatment of the solid tumours and some of the non-malignant diseases. The haematopoietic stem cell transplantation has an influence on the course of the disease and the quality of life as any other curative method. The authors explore the quality of life in 12 adult patients with acute myeloid leukaemia undergoing autologous progenitor stem cell transplantation at the Department of Clinical Haematology of the 2nd Department of Internal Medicine of Charles University Hospital in Hradec Králové. 

Methods and Results.
The European Quality of Life Questionnaire EQ-5D was used in evaluating effects of the selected healthy and psychosocial aspects on the quality of life (age, sex, level of education, religion, smoking abuse, polymorbidity, marital status and lapse time from transplantation). The results show that quality of life significantly depends on the age, level of education, smoking abuse, religion and polymorbidity. Effects of other aspects on the quality of life were not revealed. 

Conclusions.
The global quality of life in our adult patients with acute myeloid leukaemia undergoing autologous progenitor stem cell transplantation at the Department of Clinical Haematology of 2nd Department of Internal Medicine of Charles University Hospital in Hradec Králové is on greatly good level (mean EQ-5D score was 75,1 % and mean EQ-5D VAS was 67,5 %). 

Key words:
quality of life, acute myeloid leukaemia, haematopoietic stem cell transplantation, quality of life questionnaire.