Menstrual Cycle Phase and Therapeutic Response to Neuroleptic Treatment inFemale Patients with Schizophrenia

Czech version

Authors: I. Vaňurová; A. Yamamotová
Authors‘ workplace: Psychiatrické centrum, Praha Ústav normální, patologické a klinické fyziologie 3. LF UK, Praha
Published in: Čas. Lék. čes. 2001; : 668-670
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Overview

Background.
The low estrogen level is associated with the worsening of the psychotic symptoms in fe males withschizophrenia. We tested the hypothesis that the patients admitted to the hospital in the low-estrogen (low-E) phaserequire lower neuroleptic dosage and shorter length of hospital stay than the patients admitted in the high-estrogen(high-E) phase.Methods and Results. 51 female patients with schizophrenia were divided into two groups according to theirmenstrual cycle phase at admission and according to the type of neuroleptic treatment during their hospitalisation.53 % of them were admitted in the low-E phase. The Student T-test was used for the analysis. The patients of thelow-E phase group had lower daily dosage of typical neuroleptics (p

Key words:
schizophrenia, menstrual cycle, estrogen.

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Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management

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Article was published in

Journal of Czech Physicians

2001 Issue 21

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