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Ethylene Glycol Poisoning


Authors: J. Večeř;  H. Kubátová;  J. Charvát;  M. Souček;  M. Kvapil
Authors‘ workplace: Interní klinika 2. LF UK a FNM, Praha
Published in: Čas. Lék. čes. 2001; : 381-383
Category:

Overview

Ethylene glycol is a common substance in various antifreeze preparations. Intoxication is caused by ingestion either as a suicide attempt or by an accident. The clinical course of intoxication always severe, however, immediate lauching of proper treatment can reverse the poor prognosis. Intoxication clinically proceeds in three stages: 1. Depressive CNS disturbances that can lead to coma. 2. Organ manifestations. 3. Acute renal failure. The case report of 46-year-old man admitted after ingestion of ethylene glycol in suicidal attempt summarises the essential principles of therapy - monitoring of vital functions, administration of ethanol solution as an antidote and hemodialysis to remove toxic components.

Key words:
ethylene glycol, antidote

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Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management
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