Humoral Profile in Patients with Severe Aortic Stenosis
Authors:
J. Hrudová; A. Linhart; V. Vondráček; J. Humhal; F. Holm; M. Jáchymová; J. Ort; Z. Marečková; K. Horký
Authors‘ workplace:
II. interní klinika 1. LF UK a VFN, Praha
Published in:
Čas. Lék. čes. 2000; : 74-78
Category:
Overview
Background.
While the effect of neurohormones is often studied in congestive heart failure, their role in aorticstenosis needs to be elucidated.Methods. 54 consecutive patients with symptomatic aortic stenosis without overt heart failure were studied at theage of 64.4±9.3 yrs with echocardiography, x-ray and catheterization. Levels of circulating atrial natriuretic factorendothelin-1, catecholamines, plasma renin activity, immunoreactive insulin and C-peptide were assessed, relatedto hemodynamic data and compared to those in 23 healthy controls, aged 59.2±12.8 yrs.Results. Patients had significantly higher plasma levels of endothelin-1 (z-value 0.64±1.19, p=0.019), atrialnatriuretic factor (z-value 2.46±2.46, p
Key words:
aortic stenosis, left ventricular hypertrophy, neurohormones, endothelin-1, pulmonary hypertension
Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain managementArticle was published in
Journal of Czech Physicians
Most read in this issue
- Appetite Suppressants and Pulmonary Hypertension
- Maternal Bonding and Wholesome Life Style During the Pregnancy
- Ethics and Statistics Š Data Tortuning
- Beta-carotene in the Prevention of Civilisation Diseases