Effects of Insulin in High-Renin and Low-Renin Hypertension
Authors:
G. Šindelka; J. Widimský; M. Prázný; Z. Kasalová; J. Škrha
Authors‘ workplace:
III. interní klinika 1. LF UK a VFN, Praha
Published in:
Čas. Lék. čes. 1999; : 205-208
Category:
Overview
Background.
Setback in insulin resistance has been described in patients with essential hypertension. The aim ofour study was to verify at the receptor and postreceptor levels the presence of insulin resistance in patients with highor low renin activity.Methods and Results. Six patients with the renal artery stenosis (20 to 65 years, average age was 51 ± 12 years,BMI: 27 ± 2.0 kg.m2) and six patients with primary hyperaldosteronism (28 to 61 years, average age was 50 ± 13years, BMI: 26.9 ± 3.2 kg.m2) were investigated. Their diagnose was confirmed by laboratory examination, computertomography, and duplex sonography. Blood pressure was monitored for 24 hours with Spacelab tonometer (SBP:161 ± 29 mmHg, DBP: 98 ± 12 mmHg versus SBP: 168 ± 21 mmHg, DBP: 103 ± 9 mmHg; plasma renin activitywas 8.1 ± 5.6 versus 0.3 ± 0.4 ng.ml-1.h-1, p
Key words:
renin activity, primary hyperaldosteronism, clamp.
Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain managementArticle was published in
Journal of Czech Physicians
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