Pathophysiology of Diabetic Nephropathy

Czech version

Authors: V. Chábová
Authors‘ workplace: I. interní klinika 1. LF UK a VFN, Praha
Published in: Čas. Lék. čes. 1999; : 392-395
Category:

Overview

The epidemic increase of diabetic nephropathy stimulated also the interest in pathophysiological mechanisms thatlead to the development of the disease. The main interest is concentrated on the glycosylation of proteins and lipids,activation of intracellular enzyme cascades (protein kinase C, aldosoreductase) and the effect of vasoactivecompounds (NO, prostanoids, angiotensin II) and growth factors. Cytokines are also of great importance. Every newpiece of information is used in search for new modes of therapy, but most of them remain at the stage of experiments.

Key words:
diabetic nephropathies, protein kinase C, aldosoreductase, prostanoids, nitric oxide, cytokines.

Full text is not available online.

If interested in a scan of this journal, contact NTO ČLS JEP.

Labels

Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental Hygienist

Moist Healing of Chronic Wounds

Detection of Mosaicism in Turner’s Syndrome by Fluorescence insitu Hybridization (FISH)

Heterogeneity in Four Families with MERRF Syndrome

Influence of Negative Interference of Pathological Bilirubin Levelson Assessment of Serum Creatinine Concentration

Article was published in

Journal of Czech Physicians

1999 Issue 13

Download issue PDF