Problems of Substitution Treatment in Opiate Dependence and Clinical Importance of Methadone

Czech version

Authors: H. Wilczek
Authors‘ workplace: III. interní klinika 1. LF UK a VFN, Praha
Published in: Čas. Lék. čes. 1998; : 725-728
Category:

Overview

The author presents a review of experience with substitution treatment in opiate dependence. Methadone treatment is most frequently used. An individual daily dose and long-term substitution are desirable for stabilization and motivation of patients included in the methadone programme. Interaction of methadone with some drugs affects the methadone metabolism and calls for a change of the methadone dose and must not be omitted. In addition to methadone there are also other types of pharmacotherapy of opiate dependence (acetylmethadol, buprenorphine). In the Czech Republic in 1997 in the General Faculty Hospital Prague the methadone programme was started. The importance of methadone substitution treatment is beyond doubt and involves improvement of the psychosocial and health status of addicts, gives an opportunity of resocialization and reintegration into society.

Key words:
drug addiction, treatment of opiate dependence, substitution treatment, drug interactions of methadone, methadone programme in the Czech Republic.

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Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management

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Article was published in

Journal of Czech Physicians

1998 Issue 23

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