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Iron metabolism and its regulations


Authors: D. Vyoral 1,2;  J. Petrák 1,2
Authors‘ workplace: Ústav hematologie a krevní transfuze Praha, ředitel prof. MUDr. Marek Trněný, CSc. 1;  Ústav patologické fyziologie 1. lékařské fakulty UK Praha, přednosta prof. MUDr. Emanuel Nečas, DrSc. 2
Published in: Vnitř Lék 2012; 58(Suppl 2): 115-126
Category:

Overview

Iron is an indispensable element. As a catalytical center in many Fe metalloproteins it participates in almost all biochemical pathways. This element, however is able to initiate the generation of toxic free radicals. This review article summarizes the available know­ledge on the mechanisms, regulations and disorders of iron absorption, transport and storage.

Key words:
iron – iron metabolism


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