Glucocorticoid‑induced osteoporosis treatment algorithm

Czech version

Authors: J. Payer; Z. Killinger; K. Brázdilová
Authors‘ workplace: V. interná klinika Lekárskej fakulty UK a FNsP Bratislava, Slovenská republika, prednosta prof. MUDr. Juraj Payer, CSc.
Published in: Vnitř Lék 2009; 55(5): 506-511
Category: Reviews

Overview

An excess amount of glucocorticoids represents the primary and most frequent etiological factor influencing secondary osteoporosis. The patients receiving glucocorticoids, but also those with the endogenous form of hypercorticism are at high risk for the loss of bone density, with the subsequent occurrence of pathological fractures. In this review, we summarize the currently available methods of prevention and the treatment of glucocorticoid‑induced osteoporosis (GIO). We also include a proposal for both prophylactic and therapeutic approach that takes into account the risk factors typical for long‑term users of glucocorticoids.

Key words:
glucocorticoid‑induced osteoporosis –⁠ bone density –⁠ osteoporotic fractures –⁠ calcium and vitamin D –⁠ bisphosphonates –⁠ teriparatide

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