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Metabolic bone diseases and diabetes


Authors: P. Řehořková
Authors‘ workplace: Endokrinologická ambulance, Hradec Králové
Published in: Vnitř Lék 2006; 52(5): 485-487
Category: Diabetes and other subjects (infection, dermatovenerology and rheumatology) Hradec Králové 3 to 4 June 2005

Overview

Generalized osteoporosis, as one of the metabolic bone diseases, is often diagnosed in diabetics as late as after their first fracture. Alterations of bone metabolism should be therefore taken into account also in early stages of the basic disease. The risk of osteoporosis development is relatively high even in younger age groups of type 1 diabetics who suffer from defect of bone regeneration. In type 2 diabetics, the fractures are predominantly caused by more frequent falls and alterations of bone quality with normal or higher bone density. Therapy of osteoporosis in diabetics should include specific treatment regimes, supplementation with vitamin D and calcium, or an active antiosteoporotic therapy treating the basic disease.

Key words:
diabetes mellitus – osteoporosis – bone mineral density – peak bone mass – osteoblasts


Sources

1. Brown SA, Sharpless JL. Osteoporosis: An under-appreciated complication of diabetes. Clin Diab 2004; 22: 10-20.

2. Hadjidakis DJ et al. Diabetes and premature menopause: is their co-existence detrimental to the skeleton? EJE 2005; 152: 437-442.

3. Roman DA et al. Effects of dietary intake and life style on bone density in patients with diabetes mellitus type 2. Ann Nutr Metab 2004; 48: 142-145.

4. Isaia G et al. High prevalence of hypovitaminosis D in female type 2 diabetic population. Diab Care 2001; 24: 1496.

5. Harris SS. Vitamin D in type 1 diabetes prevention. J Nutr 2005; 135: 323-325.

Labels
Diabetology Endocrinology Internal medicine

Article was published in

Internal Medicine

Issue 5

2006 Issue 5

Most read in this issue
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