Authors: P. Řehořková Authors‘ workplace: Endokrinologická ambulance, Hradec Králové Published in: Vnitř Lék 2006; 52(5): 485-487 Category: Diabetes and other subjects (infection, dermatovenerology and rheumatology) Hradec Králové 3 to 4 June 2005
Generalized osteoporosis, as one of the metabolic bone diseases, is often diagnosed in diabetics as late as after their first fracture. Alterations of bone metabolism should be therefore taken into account also in early stages of the basic disease. The risk of osteoporosis development is relatively high even in younger age groups of type 1 diabetics who suffer from defect of bone regeneration. In type 2 diabetics, the fractures are predominantly caused by more frequent falls and alterations of bone quality with normal or higher bone density. Therapy of osteoporosis in diabetics should include specific treatment regimes, supplementation with vitamin D and calcium, or an active antiosteoporotic therapy treating the basic disease.
Key words: diabetes mellitus – osteoporosis – bone mineral density – peak bone mass – osteoblasts
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