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Cause of acute onset dysphagia in a geriatric female patient


Authors: Kamila Šablaturová
Authors‘ workplace: Sanatorium Jih, Ostrava
Published in: Geriatrie a Gerontologie 2021, 10, č. 4: 226-232
Category:

Overview

The case report presents an unlikely cause of acute onset dysphagia in a geriatric female patient – myasthenia gravis. Both the course of the disease as well as diagnostic procedures and ultimately fatal complications are described. Myasthenia gravis affects mostly working-age population, leading to disability in some individuals. If diagnosed in elderly patients with early bulbar and respiratory symptoms, the prognosis is far worse. It is a chronic autoimmune condition associated with fluctuating muscle weakness and fatigue. To establish the diagnosis, a careful assessment of patient’s history followed by neurologic examination, stress tests, detection of serum auto-antibodies and electromyography must be made. Myasthenia gravis treatment is long-term with the goal of clinical remission.

Keywords:

dysphagia – myasthenia gravis – muscle weakness – autoimmune disease – acetylcholine receptor


Sources

1.  Piťha J, et al. Myasthenia gravis a ostatní poruchy nervosvalového přenosu. Praha: Maxdorf 2010: 72–283.

2.  Piťha J. Myasthenia gravis. Med Praxi 2015; 12(3): 121–125.

3.  Voháňka S. Farmakoterapie myasthenia gravis. Neurol Praxi 2010; 11(2): 95–99.

4.  Piťha J. Místo farmakoterapie v léčbě myasthenia gravis. Klin Farmakol Farm 2018; 32(2): 8–12.

5.  Ehler E. Neuromuskulární nemoci. Medicína po promoci 2018; 3.

6.  Jakubíková M, Piťha J. Současný pohled na imunopatogenezi myasthenia gravis. Cesk Slov Neurol N 2015; 78/111(6): 649–654.

7.  Mantegazza R, Cavalcante P. Diagnosis and Treatment of Myasthenia Gravis. Curr Opin Rheumatol 2019; 31(6): 623–633.

8.  Piťha J. Praktické zkušenosti s klinickou diagnostikou myasthenia gravis. Neurol Praxi 2010; 11(2): 90–94.

9.  Piťha J, Bednařík J, Zapletalová O, et al. Klinický standard pro diagnostiku a léčbu myasthenia gravis. Cesk Slov Neurol N 2012; 75/108(2): 242–252.

10.  Piťha J. Klinické aspekty při léčbě myasthenia gravis. Neurol Praxi 2016; 17(3): 158–162.

11.  Špalek P. Myasthénia gravis. Cesk Slov Neurol N 2008; 71/104(1):7–24.

12.  www.myastheniagravis.cz

13.  Piťha J. Refrakterní myasthenia gravis – klinická charakteristika a možnosti biologické léčby. Cesk Slov Neurol N 2019; 82/115(5): 490–495.

14.  Menon D, Barnet C, Bril V. Novel Treatments in Myasthenia Gravis. Front Neurol 2020; 11: 538.

15.  Kalvach Z, Zadák Z, Jirák R, et al. Geriatrie a gerontologie. Praha: Grada Publishing 2004: 711–712.

16.  Topinková E. Geriatrie pro praxi. Praha: Galén 2005: 103–105.

Labels
Geriatrics General practitioner for adults Orthopaedic prosthetics
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