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Results of the Czech Myeloma group project CRAB I


Authors: V. Maisnar 1;  J. Straub 2, za Českou myelomovou skupinu
Authors‘ workplace: IV. Interní hematologická klinika LF UK a FN, Hradec Králové 1;  1. interní klinika 1. LF UK a VFN, Praha 2
Published in: Prakt. Lék. 2025; 105(3): 114-119
Category: Of different specialties

Overview

Multiple myeloma is the second most common blood cancer in the Czech Republic and its incidence is still increasing. Experience from everyday clinical practice shows that up to half of patients with multiple myeloma start treatment late due to late diagnosis. The original CRAB project of the Czech Myeloma Group was aimed at improving this fact. The current article summarizes the results of the questionnaire part of the CRAB II project, which should be followed by an extensive information campaign on the symptoms of the disease, including the recommended examination procedure in case of suspicion of their possible connection with this serious disease. Improvements in the diagnostics of multiple myeloma, especially with regard to early diagnosis, and the shift of modern treatment procedures to the first line of treatment should lead to further prolongation and at the same time improvement in the quality of life of patients in the future.

Keywords:

Multiple myeloma – diagnostics – CRAB project


Sources
  1. Hájek R, Maisnar V, Minařík J, a kol. Diagnostika a léčba mnohočetného myelomu. Transfuze Hematol Dnes 2023; 29(Suppl 2): 1–142.
  2. Rajkumar SV, Dimopoulos MA, Palumbo A, et al. International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. Lancet Oncol. 2014; 15(12): e538–e548.
  3. Arends M, van Dussen L, Biegstraaten M, et al. Malignancies and monoclonal gammopathy in Gaucher disease; a systematic review of the literature. Br J Hematol. 2013; 161(6): 832–842.

adresa pro korespondenci:
prof. MUDr. Vladimír Maisnar, Ph.D., MBA
IV. interní hematologická klinika, FN
a LF UK Hradec Králové
Sokolská 581, 500 05 Hradec Králové
e-mail:
vladimir.maisnar@fnhk.cz

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