Telomeres and the influence of lifestyle on their length

Czech version

Authors: I. Klimešová
Authors‘ workplace: Fakulta tělesné kultury UP v Olomouci, Katedra přírodovědních věd v kinantropologii, Vedoucí: prof. RNDr. Miroslav Janura, PhD.
Published in: Prakt. Lék. 2011; 91(12): 734-737
Category: Of different specialties

Overview

Over the past 50 years scientists have made substantial progress in understanding the processes at the cellular and molecular levels. Yet many ongoing processes in the cell still remain unclear. Thanks to the unique properties of telomeres, end segments of chromosomes are at the forefront of research. Not all processes that take place in these structures have been explained, but they present possible potential to protect the cells against aging, as well as in the understanding and treatment of tumour growth.

Telomeres are the chromosomal ends to preserve DNA integrity and chromosomal stability. Shortening of telomere length induces cell damage. Human telomere length is influenced by both genetic and environmental factors and it is closely related to aging and the development of certain diseases.

The study summarizes the results of work focused on the impact of exercise and diet on the length of telomeres. These studies have shown that various forms of exercise and diet modify the length of telomeres.

Key words:
telomeres, exercise, nutrition.

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