#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Extraintestinal symptoms of coeliac disease


Authors: L. Franeková;  M. Sedláčková
Authors‘ workplace: Fakultní Thomayerova nemocnice s poliklinikou, Praha ;  Primář: MUDr. Marie Sedláčková ;  Revmatologické a rehabilitační oddělení
Published in: Prakt. Lék. 2008; 88(4): 240-243
Category: Case Report

Overview

Coeliac disease is an autoimmune disorder induced by the gliadin fraction of gluten. Intestinal symptoms in adults can be very undistinguishable whereas the extraintestinal symptoms dominate in the clinical picture of the disease. In our paper, we deal with metabolic and inflammatory joint symptoms, which can lead to the correct diagnosis and appropriate therapy of coeliac disease. To illustrate this, we present two case reports, which closely describe our diagnostic process.

Key words:
coeliac disease, malabsorption, osteomalatia, anti-transglutaminase antibodies, anti-endomysial antibodies, sacroileitis, Looser pseudofracture.


Sources

1. Bourne, J.T., Kumar, P., Huskisson, E.C. et al. Arthritis and celiac disease. Ann. Rheum. Dis. 1985, 44, p. 592-898.

2. Collin, P., Korpela, M., Hällstrom, O. et al. Rheumatic complaints as a presenting symptom in patients with coeliac disease. Scand. J. Rheumatol. 1992, 21, p. 20-23.

3. Dewar, D.H., Ciclitira, P.J. Clinical features and diagnosis of celiac disease. Gastroenterology 2005, 128, Suppl 1, p. 19-24.

4. Franeková, L., Philipp, T., Sedláčková, M. Muskuloskeletální projevy při celiakii. Čes. Revmatik. 2007, 15, s. 190-196.

5. Heel, D.A., West, J. Recent advances in coeliac disease. Gut 2006, 55, p. 1037-1046.

6. Holden, W., Orchard, T., Wordsworth, P. Enteropathic arthritis. Rheum. Dis. N. Am. 2003, 29, p. 513-530.

7. Lubrano, E., Ciacci, C., Ames, P.R.J. et al. Arthritis of coeliac disease: prevalence and pattern in 200 adult patients. Br. J. Rheumatol. 2000, 29, p. 260-263.

8. Peterová, V., Forejtová, Š. Komplexní morfologická vyšetření u nemocných s ankylozující spondylitidou. Čes. Revmatik. 2006, 14 (2), s. 70-78.

9. Selby, P.L., Davies, M., Judith, E.A. et al. Bone loss in celiac disease is related to secondary hyperparathyroidism. J. Bone. Miner. Res. 1999, 14 (4), p. 652-657.

10. Usai, P., Boi, M.F., Piga, M. et al. Adult celiac disease is frequently associated with sacroiliitis. Dig. Dis. Sci. 1995, 40, p. 1906-1908.

Labels
General practitioner for children and adolescents General practitioner for adults
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#