Authors: J. Stránský 1; J. Kynčl 2; J. Stříteský 3; M. Hořejšová 4 Authors‘ workplace: I. interní klinika FN KV a 3. LF UK, Praha přednosta prof. MUDr. J. Horák, CSc. 1; Státní zdravotní ústav Praha, Centrum epidemiologie a mikrobiologie, vedoucí doc. MUDr. B. Kříž, CSc. 2; Ústav patologie 1. LF UK, Praha přednosta prof. MUDr. C. Povýšil, DrSc. 3; II. interní klinika FN KV a 3. LF UK, Praha přednosta prof. MUDr. M. Anděl, CSc. 4 Published in: Prakt. Lék. 2005; 85(4): 207-211 Category: Of different specialties
In a retrospective study of 225 anti-HCV positive cases of chronic hepatitis C in the years 1993–2003, 83 (37%) patients received blood transfusion prior to the year 1992, and 39 (17%) were i.v. drug addicts. The authors evaluated anamnestic data on viral hepatitides B and C, alcohol intake, blood transfusion, i.v. drug addiction, internal and surgical affections. Histological examination of the liver had been performed in 129 (57%) patients. Serology was carried out by 3rd generation ELISA methods, HCV RNA was detected by the polymerase chain reaction method. Results: Acute or chronic hepatitis C suffered only 8.4% of the patients, alcohol was consumed by 45%, the most frequent ailments were obesity, cholelithiasis, and hypertension, and of surgical intervention it was gall bladder surgery, accidents, resection of the stomach and intestines. Drug addicts were significantly younger than subjects with blood transfusion (p
Key words: chronic hepatitis C – diagnostics – complications.
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