Reversibility of type 1 hepatorenal syndrome in patientwith acute alcoholic hepatitis complicated with acute pancreatitis after continual terlipressininfusion and albumin plasmaexpansion - Case report

Czech version

Authors: P. Jarčuška; E. Veseliny; M. Zakuciová
Authors‘ workplace: I. interná klinika FNsP a LF UPJŠ, Košice, Slovakia, prednosta doc. MUDr. T. Hildebrand, CSc.
Published in: Prakt. Lék. 2004; (9): 519-522
Category:

Overview

A 36-year-old man was admitted at 1st Department of Internal Medicine, University Hospitalin Košice because of acute alcoholic hepatitis with extremely elevated aminotransferases (ALT:113,1 kat/l, AST: 416,1 kat/l) complicated with acute pancreatitis and bilateral bronchopneumonia.Hepatorenal syndrome type 1 was diagnosed. Patient was treated by continualterlipressin infusion /1 mg daily) in combination with albumin (20 g daily) plasma expansionfor 15 days. The therapy led to serum creatinine, serum sodium and kidney function normalisation.Diuresis and natriuresis increase was induced by the therapy. Acute pancreatitis andbronchopneumonia were recovered. Normalised kidney functions and improved liver functionshad persisted after termination of therapy.

Key words:
acute alcoholic hepatitis - acute pancreatitis - hepatorenal syndrome - terlipressin- albumin.

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