Authors: Strnad L.'; L. Gladkij 2; A. Stožický 3 Authors‘ workplace: Neurologická klinika IPVZ - FTN, Praha Oddělení patologie FTN, Praha Published in: Prakt. Lék. 2001; (12): 45-48 Category:
The authors present two cases of patients suffering from the Sporadic form of Creutzfeldt-Jakob's disease during the last year. The most important diagnostic signs in the clinical picture were dementia, cerebellar syndom, quadruspasticity and myoclonus. During repeated examinations the typical development of the EEG finding was found. Other auxiliary examinations were non-specific. In the post-mortem finding typical changes of spongiform dystrophy were found. The authors discussed possibilities of immunohistochemical examinations. In the described cases the Sporadic form of CJD (sCJD) was involved. Attention is drawn to differences of the Sporadic form and new variant forms of CJD (nvCJD).
Key words: Creutzfeldt-Jakob's diseases, Sporadic form
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