24-hour Monitoring of the Blood Pressure during Betaxolol Treatment in Patients with Recent Mild an Moderate Hypertension

Czech version

Authors: I. Řiháček; M. Souček; J. †julínek; T. Kára; M. Orban; P. Fráňa
Authors‘ workplace: I. interní kardio-angiologická klinika FN u svaté Anny, Masarykova univerzita, Brno, přednosta prof. MUDr. J. Toman, CSc.
Published in: Prakt. Lék. 2000; (12): 699-702
Category:

Overview

Reduction of the blood pressure (BP) for 24 hours prevents damage of the target organs. The objective of the submitted work was to assess the 24-hour effectiveness of the beta-blocker bexolol, its effect on occasional and 24-hour systolic (sBP), diastolic (dBP), mean blood pressure (MBP) and pulse pressure (PP) and pulse rate (HR). The authors followed up circadian changes of the BP and compared values of basic laboratory parameters before and after treatment. In the investigation 50 patients were included, mean age 39±10.5 years with recently diagnosed mild and moderate hypertension. After three months of betaxolol treatment a statistically significant decline of sBP, dBP, MBP and HR were recorded by 24-hour monitoring of the BP (-12 mm Hg sBP, -11 mm Hg dBP, -12 mm Hg MBP, -11 strokes/minute HR, p

Key words:
hypertension - 24-hour monitoring of the BP - circadian variability of BP - beta-blocker.

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