Occupational Damage of the Kidney and Urinary Pathways

Czech version

Authors: J. Kohout; Z. Ouda
Authors‘ workplace: Klinika pracovního lékařství FN, Plzeň, přednosta doc. MUDr. J. Kohout, CSc. Urologická klinika FN, Plzeň, přednosta doc. MUDr. Z. Ouda, CSc.
Published in: Prakt. Lék. 1999; (9): 514-516
Category:

Overview

The authors analyze the action of the most important occupational nephrotoxic substances. Inacute intoxications tubular damage or even necrosis is found which may be caused by arsenictrihydride, bivalent mercury compounds, cadmium, chromium, glycols halogenated hydrocar-bons and uranium. In chronic exposure tubular damage is more frequent (lead, mercury,cadmium, chromium, nickel, toluene, styrene, trichloroethylene) than glomerular damage(mercury, styrene, trichloethylene). Some substances and working procedures may play a partalso in the etiopathogenesis of malignant tumours of the kidneys, urinary bladder and prostate.

Key words:
acute tubular necrosis - chronic tubular and glomerular damage - renal carcinoma- carcinoma of the urinary bladder - carcinoma of the prostate.

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