Search of Non-related BoneMarrow Donors and Development of Indications for „Non-related“ Transplantations in the CzechRepublic in 1992-1998

Overview

During the period from 1992 till Sept. 1, 1998 the number of applications of Czech transplan-tation centres for „non-related“ bone marrow donors was recorded, as well as indications fortransplantations from non-related subjects, the time needed to find a donor and the successrate among Czech volunteers. The number of applications for a non-related bone marrow donorincreased every year whereby indications for transplantation were consistent with internatio-nal experience. The time needed to find a donor declined every year and during the last year ofthe investigation it was less than one month in 70% of the applications. For almost 20% of thepatients a non-related donor was found among Czech volunteers. In 13 patients the transplan-tation was not implemented although a donor was found because of the patient’s death orrelapse of the basic disease. Based on hitherto assembled experience it may be in futureconsidered most important to start in time with the search for a non-related donor whena suitable donor is not found in the family, and ensure better collaboration between indicatingtransplantation centres and registers.

Key words:
bone marrow transplantations among non-related subjects - indications - bonemarrow donorship.