Uric acid: pathophysiological implications

Authors: Fedor Šimko 1;  Andrej Dukát 2
Authors‘ workplace: Ústav patologickej fyziológie LF UK v Bratislave 1;  V. interná klinika LF UK a UNB, Nemocnica Ružinov, Bratislava 2
Published in: Forum Diab 2019; 8(1): 11-14


Pathophysiologic relations of hyperuricaemia are complex and associations are cinfirmed with cardiovascular, renal, methabolic diseases, endothelial dys-function, arterial hypertension, systemic inflammation, proaggregation and oxidative stress. From the first scientific report about hyperuricaemia in 1871 repeatedly causal relationship of increased uric acid level to several organism´s systems is described.


acid uric – hyperuricemia – pathophysiology

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Diabetology Endocrinology Internal medicine
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