Botulism – a rare but still present, life-threatening disease

Authors: H. Ambrožová
Authors‘ workplace: Klinika infekčních nemocí 2. LF UK a Nemocnice Na Bulovce, Praha
Published in: Epidemiol. Mikrobiol. Imunol. 68, 2019, č. 1, s. 33-38
Category: Review Article


Botulism caused by toxins of Clostridium botulinum and other neurotoxic clostridia is a rare but life-threatening disease with neurological symptoms. Food-borne botulism (food poisoning) is the most common type worldwide; rarely, wound botulism, infant botulism, or botulism of unknown etiology may also occur. Botulism is a very rare disease in the Czech Republic as well, with only nine cases reported since 2008 (EPIDAT). These were mostly sporadic cases of food-borne botulism except a small family outbreak with three cases due to the consumption of homemade pork pate (2013). This outbreak prompted the creation of a national standby supply of life-saving anti-infective drugs in Prague. This article reviews the etiology, epidemiology, clinical manifestations, diagnosis, and therapy of botulism.


botulism – Clostridium botulinum – clinical picture – diagnosis


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