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Pseudotumors of the testis and testicular adnexa


Authors: O. Hes;  M. Michal
Authors‘ workplace: Oddělení speciální diagnostiky ŠPAÚ, Lékařská fakulta a Fakultní nemocnice Plzeň
Published in: Čes.-slov. Patol., 48, 2012, No. 3, p. 146-149
Category: Reviews Article

Overview

A review article dealing with the most common pseudotumors of the testicular region. Nodules of immature tubules, pseudotumors in adrenogenital syndrome, fibromatous periorchitis, pseudosarcomatous myofibroblastic proliferation, posstraumatic mesothelial glandular inclusions and vasitis nodosa are described in detail, including morphologic and immunohistochemical features, altogether with a differential diagnostic approach. 

Key words:
testis – testicular adnexa – nodules of immature tubules – pseudotumors in adrenogenital syndrome – fibromatous periorchitis – pseudosarcomatous myofibroblastic proliferation – posstraumatic mesothelial glandular inclusions – vasitis nodosa


Sources

1. Rosai J. Rosai and Ackerman‘s Surgical Pathology. Edinburg, London: Elsevier, Mosby, 10th ed. 2011.

2. Ulbright TM, Amin MB, Young RH. Tumors of the testis, adnexa, spermatic cord, and scrotum. Washington D.C., AFIP, 1999.

3. Halley JB. The growth of Sertoli cell tumors: a possible index of differential gonadotropin activity in the male. J Urol 1963; 90: 220-229.

4. Barghorn A, Alioth H-R, Hailemariam S, Bannwart F, Ulbright TM. Giant Sertoli cell nodule of the testis: distinction from other Sertoli cell lesions. J Clin Pathol 2006; 59: 1223-1225.

5. Govender D, Sing Y, Chetty R. Sertoli cell nodulus in the undescended testis: a histochemical, immunohistochemical and ultrastructural study of hyaline deposits. J Clin Pathol 2004; 57: 802-806.

6. Johnson RE, Scheithauer B. Massive hyperplasia of testicular adrenal rests in a patient with Nelsonęs syndrome. Am J Clin Pathol 1982; 77: 501-507

7. Krieger DT, Samojlik E, Bardin CW. Cortisol and androgen secretion in a case of Nelson’s syndrome with paratesticular tumors: response to cyprohepatadine therapy. J Clin Endocrinol Metab 1978; 47: 837-844

8. Baranetsky NG, Zipser RD, Goebelsmann U, et al. Adrenocorticotropin-dependent virilizing paraovarian tumors in Nelson’s syndrome. J Clin Endocrinol Metab 1979; 49: 381-386.

9. Verdonk C, Guerin C, Lufkin E, Hodgson SF. Activation of virilizing adrenal rest tissues by excessive ACTH production. An unusual presentation of Nelson’s syndrome. Am J Med 1982; 73: 455-459.

10. Wild RA, Albert RD, Zaino RJ, Abrams CS. Virilizing paraovarian tumors: a consequence of Nelson’s syndrome? Obstet Gynecol 1988; 71: 1053-1056.

11. Davis JM, Woodroof J, Sadasivan R, Stephens R. Case report: congenital adrenal hyperplasia and malignant Leydig cell tumor. Am J Med Sci 1995; 309: 63-65.

12. Battaglia M, Ditonno P, Palazzo S, Bettochi C, Selvaggio O, Garofalo L, Selvaggi FP. Bilateral tumors of the testis in 21-alpha hydroxylase deficiency without adrenal hyperplasia. Urol Oncol 2005; 23: 178- 180.

13. Rutgers JL, Young RH, Scully RE. The testicular „tumor“ of the adrenogenital syndrome. Am J Surg Pathol 1988; 12: 503-513.

14. Polsky EG, Ray Ch, Dubilier LD. Diffuse fibrous pseudotumor of the tunica vaginalis testis, epididymis and spermatic cord. J Urol 2004; 171: 1625-1626.

15. Seethala RR, Tirkes AT, Weinstein S, Tomaszewski JE, Malkowitcz SB, Genega EM. Diffuse fibrous pseudotumor of the testicular tunics associated with an inflamed hydrocele. Arch Pathol Lab Med 2003; 127: 742-744.

16. Nistal M, Paninagua R, Torres A, Hidalgo L, Regadera J. Idiopatic peritesticular fibrosis associated with retroperitoneal fibrosis. Eur Urol 1986; 12: 64-68.

17. Vates TS, Ruemmler-Fisch Ch, Smilow PC, Fleisher MH. Benign fibrous testicular pseudotumors in children. J Urol 1993; 150: 1886-1888.

18. Watson RA, Harper BN. Paratesticular fibrous pseudotumor in a patient with Gorlinęs syndrome: nevoid basal cell carcinoma syndrome. J Urol 1992; 148: 1254-1255.

19. Hamilton FA, Persad RA, Webb RJ, Ball RY. Fibrous pseudotumor of the tunica vaginalis following vasectomy. J Urol Pathol 1997; 6: 243-248.

20. Weiss SH, Goldblum JR, Folpe AL. Enzinger and Weissęs Soft Tissue Tumors, Philadelphia, Mosby, 5th ed., 2008.

21. Donnellan R, Bramdev A, Chetty R. A paratesticular pseudosarcomatous myofibroblastic proliferation. A case report. Int J Surg Pathol 1998; 6: 235-238.

22. Kraus MD, Guillou L, Fletcher CD. Well-differentiated inflammatory liposarcoma: an uncommon and easily overlooked variant of a common sarcoma. Am J Surg Pathol 1997; 21: 518-527.

23. Amin MB. Selected other problematic testicular and paratesticular lesions: rete testis neoplasms and pseudotumors, mesothelial lesions and secondary lesions. Mod Pathol 2005;18(Suppl 2): 131-145.

24. Michal M, Hes O, Kazakov DV. Mesothelial glandular structures within pseudosarcomatous proliferative funiculitis. A diagnostic pitfall. Report of 17 cases. Int J Surg Pathol 2008; 16: 48-56.

25. Olson AL. Vasitis nodosa. Am J Clin Pathol 1971; 55: 364-368.

26. Balogh K, Travis WD. The frequency of perineurial dusctules in vasitis nodosa. Am J Clin Pathol 1984; 82: 710-713.

27. Goldman RL, Azzopardi JG. Benign neural invasion in vasitis nodosa. Histopathology 1982; 6: 309-315.

28. Civantos F, Lubin J, Rywlin AM. Vasitis nodosa. Arch Pathol 1972; 94: 355-361.

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Anatomical pathology Forensic medical examiner Toxicology
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