Melanocytic pseudotumors
Authors:
L. Pock
Authors‘ workplace:
Dermatohistopatologická laboratoř, Praha
Published in:
Čes.-slov. Patol., 48, 2012, No. 3, p. 127-134
Category:
Reviews Article
Overview
Melanocytic lesions are one of the most difficult chapters of dermatopathology when you consider the number of entities, high frequency of excisions and serious consequences of a mistaken diagnosis. Melanocytic pseudotumours, benign lesions simulating melanoma, are its subgroup. At present, it is possible to designate 25 entities and situations. Spitzoid, combined, spindle cell and hyperpigmented lesions belong to the most common problems in the differential diagnosis. Not only histological but also clinical – dynamical and morphological – criteria ought to be taken into account for the maximally correct diagnosis. In heterogeneous lesions it is necessary, although difficult, to try to find the individual components of the lesion in sections. For this reason it is important to know the macroscopy of a particular lesion. In cases where it is impossible to make a reliable decision between benignity and malignancy it is necessary to choose the optimal therapeutic approach in collaboration with a clinical physician.
Keywords:
melanoma simulators – histology - borderline melanocytic lesions – diagnostic approach
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Labels
Anatomical pathology Forensic medical examiner ToxicologyArticle was published in
Czecho-Slovak Pathology
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