Inflammatory Stromal Reaction in Epithelial Neoplasias of the Uterine Cervix in Correlation with HPV Infection
Authors:
M. Tichý 1; V. Tichá 1; Z. Kolář 1; S. Brychtová 1; J. Bystroň 2; L. Kotršová 3; E. Hamšíková 4; J. Dušek 1; V. Vonka 4
Authors‘ workplace:
Ústav patologie LF UP, Olomouc, přednosta prof. MUDr. J. Dušek, CSc. 2 Oddělení klinické imunologie FN, Olomouc, vedoucí doc. MUDr. E. Weigl, CSc. 3 Porodnicko-gynekologická klinika FN, Olomouc, přednosta prof. MUDr. M. Kudela, CSc. 4 Ústav hematologie a
1
Published in:
Čes.-slov. Patol., , 1998, No. 4, p. 142-148
Category:
Overview
260 cases of women with epithelial neoplasias of the uterine cervix were studied:
HPV infection was detected by DNA in situ hybridization and serology, simultaneously structure and intensity of stromal inflammatory reaction (SR) were evaluated (semiquantitatively) as well as standard clinical immunological parametres investigated by serology. Results proved the same character of SR in intraepithelial lesions and invasive carcinomas and the intensity of SR increasing in relati- on to the gravity of epithelial dysplasia. There was not found any significant difference in SR between cases with detected HPV infection and cases lacking it. Summarized immunological parametres were in limits of normal reference range.
Key words:
cervical intraepithelial neoplasia - cervical carcinoma - inflammatory stromal reaction - papillomaviruses
Labels
Anatomical pathology Forensic medical examiner ToxicologyArticle was published in
Czecho-Slovak Pathology
1998 Issue 4
Most read in this issue
- Low Grade Malignant Fibromyxoid Sarcoma
- Diagnosis of Early Phase Diffuse Axonal Injury by Immunohistochemical Methods
- The System for Digital Image Grabbing and Computer Processing for Electron Microscope Tesla BS500
- Ultrastructural Observations on Neuroblastic Tumors in Childhood: A Study of Tumor Cell Differentiation and Regression on 89 Cases