Fatal meningococcal sepsis caused by Neisseria meningitidis serogroup W
Authors:
L. Krbková 1; M. Fedora 2; J. Pavelka 1; P. Křížová 3; K. Labská 4; Z. Vacková 3
Authors‘ workplace:
Klinika dětských infekčních nemocí, LF MU a FN Brno
1; Klinika dětské anesteziologie a resuscitace, LF MU a FN Brno
2; Národní referenční laboratoř pro meningokokové nákazy, Státní zdravotní ústav, Praha
3; Národní referenční laboratoř pro herpetické viry, Státní zdravotní ústav, Praha
4
Published in:
Čes-slov Pediat 2017; 72 (5): 322-324.
Category:
Case Report
Overview
We present a fatal course of meningococcal infection. The patient was a seventeen-year-old girl with one-day history of abdominal pain and diarrhoe. At the time of admission, she was unconscious (Glasgow Coma Scale 3), ecchymoses were present on the skin, hypotension with non-palpable peripheral pulsation developed and capillary return was prolonged. Leukopenia, thrombocytopenia, anemia, coagulopathy and severe lactic acidosis dominated in laboratory findings. The girl died of hypodynamic septic shock refractory to the treatment 4 hours after admisson. Neisseria meningitidis was confirmed by a noncultivation method from the spleen tissue and the presence of capsular gene synG by rt-PCR determined the strain belonging to the serogroup W.
KEY WORDS:
meningococcal sepsis, serogroup W, multiorgan failure, quadrivalent meningococcal conjugate vaccine A, C, Y, W
Sources
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Labels
Neonatology Paediatrics General practitioner for children and adolescents Intensive Care Medicine Trauma surgeryArticle was published in
Czech-Slovak Pediatrics
2017 Issue 5
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