Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis in Children
Authors:
E. Klásková 1; V. Smolka 1; J. Dobešová 2; J. Reitinger 1; J. Wiedermann 1; L. Vítková 1; E. Kaďůrková 1
Authors‘ workplace:
JIRP, Dětská klinika, FN a LF UP, Olomouc
přednosta prof. MUDr. V. Mihál, CSc.
1; Klinika chorob kožních a pohlavních, FN a LF UP, Olomouc
přednostka doc. MUDr. D. Ditrichová, CSc.
2
Published in:
Čes-slov Pediat 2007; 62 (1): 31-36.
Category:
Case Report
Overview
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are acute mucocutaneous diseases which become manifest as typical skin and mucous membrane lesions. It is etiologically a multi-factorial disease. The authors describe two case reports of patients with Stevens-Johnson syndrome and toxic epidermal necrolysis. A combined anti-epileptic treatment with lamotrigin, valproate and clonazepam was probably closely associated with the development of TEN in the first patient. In the second patient mycoplasma was the triggering moment in the development of SJS. An early diagnosis and correct therapy favorably influence the development of complications and mortality in the patients.
Key words:
Stevens-Johnson syndrome, toxic epidermal necrolysis, lamotrigin, mycoplasma infection
Labels
Neonatology Paediatrics General practitioner for children and adolescentsArticle was published in
Czech-Slovak Pediatrics
2007 Issue 1
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