Authors: J. Táborská 1; V. Gutová 2; A. Koubová 1; P. Pazdiora 3; V. Lebedová 4 Authors‘ workplace: Infekční klinika Fakultní nemocnice, Plzeň přednostka MUDr. J. Táborská, PhD. 1; Ústav imunologie a alergologie LF UK, Plzeň přednosta doc. MUDr. P. Panzner, CSc. 2; Ústav epidemiologie LF UK, Plzeň vedoucí doc. MUDr. P. Pazdiora, CSc. 3; Národní referenční laboratoř pro hemofilové nákazy, Centrum epidemiologie a mikrobiologie, SZÚ, Praha vedoucí MUDr. V. Lebedová 4 Published in: Čes-slov Pediat 2005; 60 (5): 288-292. Category: Case Report
The authors present a case report of a 19-month child regularly vaccinated with three doses of the vaccine against invasive infections caused by Haemophilus influenzae type b (Hib). In spite of that the patient suffered from bacterial meningitis caused exactly by this microbial strain. The immunological examination demonstrated a deficiency of serum immunoglobulins IgA and IgG, which was probably the cause of insufficient production of antibodies against polyribosil-ribitolphosphate (PRP) antigen Hib after the vaccination and, also, the cause of the disease development. The problems in failure of vaccination against Hib are discussed.
Key words: Haemophilus influenzae type b, vaccination, meningitis
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