Analysis of Accidental Drug Intoxications in Children Hospitalized at the Children's FacultyHospital in Bratislava in the Years 1996 - 2000

Czech version

Authors: M. Kuželová ¹; S. Plačková ²; L. Kovács ³; M. Benedeková ⁴; R. Riedel ⁵; B. Cagáňová ²; J. Seginko ¹; P. Švec ¹
Authors‘ workplace: Katedra farmakológie a toxikológie FaF UK, Bratislava1 vedúci prof. MUDr. P. Švec, DrSc. Toxikologické informačné centrum, Klinika pracovného lekárstva a toxikológie LF UK, FNsP akad. L. Dérera, Bratislava2 vedúca PharmDr. S. Plačková, MPH. II. detská kli
Published in: Čes-slov Pediat 2004; (7): 341-347.
Category:

Overview

The authors analyze accidental drug intoxications in children, who were hospitalized for this diagnosis at the1st and 2nd Children's Clinics ofLF UKand Children's Clinic of Anesthesiology and Intensive Medicine (DKAIM)of Children's Faculty Hospital with Policlinic in Bratislava in the period of 1996 - 2000. The analyzed cohort (43.7%of all drug intoxications) included 129 child patients up to 6 years of age. Two-year children constituted the mostfrequent group. Flunitrazepam was the most frequent drug in accidental intoxications and the most frequentpharmacological group was that of analgesic drugs - antipyretic and antirheumatic ones. Accidental intoxicationwith paracetamol and ibuprofen formed a large group of intoxications. Children from the observed groupconsumed the preparations most frequently in a solid drug form (87.1%), color drug forms (56.1%) and preparationswrapped in blister packs (66.4%) prevailed. In the analyzed cohort there were 13 cases of serious intoxicationsand one case of heavy intoxication. Serious and heavy intoxications were most frequently encountered afterflunitrazepam.

Key words:
accidental intoxication, children, drugs, degree of intoxication

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