Authors: D. Horáková 1; J. Venháčová 2; L. Čížek 1; V. Janout 1 Authors‘ workplace: Ústav preventivního lékařství LF UP, Olomouc1 Dětská klinika LF UP a FN, Olomouc 2 Published in: Čes-slov Pediat 2003; (3): 137-140. Category:
Several international epidemiological studies were published recently dealing with the possible relationshipbetween foetal development and important chronic diseases like coronary heart disease or non-insulin dependentdiabetes in the adult age, called Barker’s hypothesis. Paper reviews the evidence that the risk of non-insulindependent diabetes in adult life may be set by nutrition and growth in fetal life. At the same time results of a smallpilot study are presented, which correlate with this hypothesis.
Key words: birth weight, insulin resistence, non-insulin dependent diabetes, Barker’s hypothesis
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