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Immunomodulation of Recurrent Urinary Tract Infections in a Paediatric Patient with VesicouretheralReflux (Case report)


Authors: F. Gazdík;  K. Gazdíková;  M. Šauša;  M. R. Piják
Authors‘ workplace: Oddelenie klinickej imunológie, Ústav preventívnej a klinickej medicíny, Bratislava, riaditeľ doc. MUDr. Š. Nyulassy, DrSc.
Published in: Čes-slov Pediat 2002; (8): 436-439.
Category:

Overview

Vesicouretheral reflux (VUR) is an inherited abnormality of the urinary tract frequently accompanied byrecurrent urinary infections. The standard therapeutical approach comprises surgical correction and consequentlong-term prophylactic antibiotic therapy. Authors present case report of a paediatric patient with VUR sufferingfrom recurrent urinary infections. The use of standard therapy failed. After assessment of secondary deficiency inT cell mediated immunity, combined immunomodulatory therapy (transfer factor, preparation Immodin inj., indose 1 inj. s.c., once weekly - 3 weeks follow up, 4th and 5th inj. in every 4 weeks lasting intervals and bacteriallysate, preparation Uro-Vaxom in dose 1 caps. daily, during the period of 3 months) was administered. High clinicalefficacy was observed with long-term (2.5 yrs) absence of urinary infection.

Key words:
immunostimulating treatment, bacterial lysate, transfer factor, relapsing uroinfection, vesicouretheralreflux

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Neonatology Paediatrics General practitioner for children and adolescents
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