Continual Monitoring of the Blood Sugar Level and its Possible Application in Paediatrics

Overview

Continuous Glucose Monitoring 5ystem (CGM5) yields dynamit data on glycaemic profiles, utilising the Glose relation of the interstitial fluid Gucose level to glycaemia. Using CGM5 authors made 42 three-day assessments in 26 children (14 boys and 12 girls, mean age 11.0 ± 4.3 years, range 0.5 -17 years). Twenty four children were treated for type 1 diabetes mellitus, one boy presented with endogenous hypoglycaemia and one girl with MODY (Maturity Onset Diabetes of the Young) Type 1. Authors analysed 116 measured days.5ufficient validity of assessment was achieved in 52 (45%) of the days. The correlation coefficient between calibrations by personal glucometers and CGM5 values was 0.83.A total of 14 hypoglycaemic episodes (7 nocturnal and 7 in daytime) were detected in six children. The majority of the nocturnal hypoglycaemias passed unrecognised (6/7). Daytime hypoglycaemias tended to be shorter than the nocturnal episodes (101 ± 108 min. vs. 33 ± 30 min., p > 0.05).Conclusion: CGM5 helps patients and physicians to determine patterns of hypoglycaemia and postprandial hyperglycaemia that may have been undetected.

Key words:
Continuous Glucose Monitoring 5ystem (CGM5), type 1 diabetes mellitus, children, hypoglycaemia