Authors: J. Gajdoš; E. Nováková 1; K. Tancárová Authors‘ workplace: Detské oddelenie NsP, Levoča Published in: Čes-slov Pediat 2000; (7): 448-451. Category:
During a four-year surveillance of haemophilus infections in the Slovak Republic 7% of all cases of invasivecases in children occurred in children under the age of 3 months. 650 paired mother-neonate samples wereexamined with the objective to assess the anti PRP Hib antibody level.The mean level of PRP antibodies was 3.16 mg/l in mothers and 2.87 mg/l in neonates. The ratio of transmissionof antibodies in individual paired sera was 17 - 98% (mean 91.7 %). 15 % of the neonate s had a level of anti PRPHib antibodies lower than 0.5 mg/l.The authors found that 15 % neonates do not have at the age of 3 months a protective level of anti PRB Hibantibodies either due to low levels in the mother or due to inadequate transmission of antibodies from the mother.
Key words: Haemophilus influenzae type b, antibodies, mother - neonates
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