Authors: J. Mourek; Vratislav Krejčí 1; L. Šmídová; R. Plavka 1; V. Šlapetová Authors‘ workplace: Fyziologický ústav 1. LF UK, Praha, vedoucí prof. MUDr. S. Trojan, DrSc. II. gynekologicko-porodnická klinika 1. LF UK, Praha, 1přednosta prof. MUDr. J. Živný, DrSc. Published in: Čes-slov Pediat 1999; (2): 82-85. Category:
In newborns born to mothers with gestational diabetes, using gas chromatography, the spectrum of serum fattyacids (from umbilical blood) just after delivery, was assessed. The newborns (n = 10) were born in term (40.1 weeksgestational age) with physiological parameters: body weight (3836 g) and length (50.1 cm). Fatty acids are expressedin % (i.e. their relative ratio) of total amount (ĺ = 100 %).The established values were compared with control data obtained in physiological newborns (n = 6).Gestational diabetes of pregnant mothers (IIIrd trimester of pregnancy) influences the fatty acid spectrum oftheir newborns:1. A significant increased percentage of saturated FA. 2. A significant decrease of polyunsaturated n-3 andn-6 acids was described. There was a decrease of important fatty acids such as arachidonic, eicosapentaenoic anddocosahexaenoic FA. The possible mechanism as well as the possible after-effects of such changes and differencesare discussed.
Key words: fatty acid spectrum, gestational diabetes, newborns
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