Relation between Sensitization to Respiratory Allergens and Bronchial Asthma, Allergic Rhinitis and Further Parameters in Patients with Atopic Eczema

Authors: J. Čelakovská 1;  K. Ettlerová 2;  K. Ettler 1;  J. Vaněčková 3;  J. Bukač 3
Authors‘ workplace: Klinika nemocí kožních a pohlavních FN a LF UK Hradec Králové přednosta doc. MUDr. Karel Ettler, CSc. 1;  Ambulance klinické imunologie a alergologie, Hradec Králové vedoucí MUDr. Květuše Ettlerová 2;  Ústav lékařské biofyziky LF UK Hradec Králové přednosta doc. Ing. Josef Hanuš, CSc. 3
Published in: Čes-slov Derm, 90, 2015, No. 5, p. 191-196
Category: Pharmacologyand Therapy, Clinical Trials


A few reports demonstrate the relationship between IgE sensitization to aeroallergens in atopic dermatitis and other allergic diseases and parameters. The objective of this study is to evaluate, if there is a significant relationship between the sensitization to common aeroallergens in atopic dermatitis patients and the occurrence of asthma bronchiale, rhinitis, and other atopic parameters. Sensitization to dust, mites, animal dander, and bird feather was examined byskin prick test and specific IgE. The relationship of sensitization to these allergens and the occurrence of asthma bronchiale, rhinitis, duration of atopic dermatitis, family history, and onset of atopic dermatitis was evaluated. We examined 288 patients – 90 men and 198 women. According to our results, IgE sensitisation to animal dander, dust and mites may increase the risk of developing asthma or rhinitis. In patients with sensitization on the feathers of birds occurs significantly more frequently the onset of atopic eczema after the 5th year of life and in these patients no relationship to the positive family history of atopy has been found.

Key words:
atopic dermatitis – inhalant allergy – mites – dust – animal dander – feather – asthma bronchiale – rhinitis – onset of atopic dermatitis – duration of eczema – family history


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